Product of the Week

Elix High-Throughput water purification system
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Merck

Elix High-Throughput water purification system

Merck, a leading science and technology company, today introduced the Elix® High-Throughput water purification system, providing laboratories with a reliable water purification solution for daily water volumes of up to 9000 liters. Designed to operate at the heart of a central water purification solution, the Elix® High-Throughput system offers full connectivity, providing authorized users real-time remote monitoring via computer, tablet or smartphone with access to all important water quality data.
 
"Merck is committed to improving laboratory workflows with innovative products like our Elix® line of water purification systems that integrate seamlessly with existing systems and require little maintenance," said Theresa S. Creasey, Head of Strategy, Marketing and Innovation at the life science business of Merck. "Our systems are also designed to decrease energy and water consumption, without sacrificing water quality or ease of use.”
 
The Elix® High-Throughput system incorporates technologies consistent in delivering optimum quality, analytical-grade water for use in regular laboratory applications and instrument feeds. The system combines Merck’s Elix® electrodeionization technology with advanced purification, including Progard® pretreatment cartridges, reverse osmosis and bactericidal UV lamp treatment. The new models include Merck’s E.R.A.™ (Evolutive Reject Adjustment) technology, which automatically optimizes water recovery and reduces water usage costs by taking feed water quality into account. The system can also be linked to a Laboratory Information Management System or Building Management System for enhanced efficiency and productivity.
 
The Elix® High-Throughput system’s easy-to-use communications interface displays all of the details needed for daily operation. A large color touch screen features storage level and dispensing information, water production and the status of system consumables, including step-by-step instructions from a system wizard for effortless replacement.

Contact:

Merck KGaA
Frankfurter Strasse 250

64293 Darmstadt

Germany

karen.tiano[at]emdmillipore.com

none

Products

GE Healthcare

Designed for efficient, small-scale purification and screening of histidine-tagged proteins from different sources.

GE Healthcare

His Mag Sepharose Ni products are magnetic beads designed for efficient, small-scale purification/screening of histidine-tagged proteins from different sources. Histidine-tagged proteins are captured using immobilized nickel ions followed by collection of the beads using a magnetic device. You can use magnetic beads to simplify sample handling during small-scale purification.

His Mag Sepharose Ni delivers:

  • High-capacity small-scale purification of histidine-tagged proteins from different sources
  • High purity and yield
  • Easy parallel screening of histidine-tagged proteins with high repeatability
  • Scalability—Simple capture of histidine-tagged proteins from small or large sample volumes (low microliter to milliliter scale)


The beads are available in three pack sizes: 2 × 1 ml 5% medium slurry, 5 × 1 ml 5% medium slurry, and 10 × 1 ml 5% medium slurry—a 1 ml 5% medium slurry is the same as 50 μl sedimented medium. A 1 ml medium slurry is sufficient for 5 purification runs according to the recommended protocol.

Together with MagRack 6, a separation tool for handling the beads in microcentrifuge tubes, up to six samples can be processed in parallel. You can easily screen a larger number of samples in parallel with high throughput on a robotic device.


Simplified handling:

The magnetic bead format has excellent properties for small-scale experiments. The high density of the beads allows rapid capture by magnetic devices while the visibility of the beads ensures reliable collection of the bound histidine-tagged proteins in the purification procedure. The characteristics of the media are summarized in Table 1. All the products are provided with protocols optimized for purification of histidine-tagged proteins.


Tabel 1. Characteristics of His Mag Sepharose Ni

  • Matrix: Highly crosslinked spherical agarose (Sepharose) including magnetite
  • Metal icon capacity: 21µmol Ni2+/ml medium
  • Binding capacity: approx. 50mg histidine-tagged protein/ml medium (approx. 500µg/purification run)
  • Particle size: 37 to 100µm
  • Working temperature: Room temperature and + 4ºC
  • Storage solution: 20% ethanol, 5% medium slurry
  • Storage temperature: Room temperature

     

Contact:

GE Healthcare Europe GmbH

Dr. Michael Walther
EMEA Marketing Manager Electrophoresis

T    + 49 2293 816 749
M   + 49 173 574 9413
F    + 49 5564 204 593

Michael.Walther[at]ge.com

www.gelifesciences.com

Mettler-Toledo

Flexible automation efficient titrations - Increase testing throughput in your lab with the single row InMotion Flex Autosampler.

Mettler-Toledo

Advanced Cleaning Sequences
Ensure clean components and no carry over with the PowerShower™ rinse and dedicated conditioning beakers. Your sensors will be properly stored and ready for analysis with the automated Park function.

Efficient Operation
Optimize efficiency in your laboratory using the LED status lights on the top of the InMotion towers. One quick look from across the lab lets you know if your autosampler is still running samples, is ready for more samples or needs your attention.

Compact and Modular
The Flex is only 42 cm wide minimizing the bench space needed to automate your titrations. Add stacking magnetic pumps on the side of the InMotion Autosampler or the insert able option boards in the back of the autosampler. Expansion requires no more space.

For more information please click here.

ProteinSimple

Gel-free. Blot-free. Hands-free. A Simple Western is the Western you know well, only simplified.

ProteinSimple

Gel-free. Blot-free. Hands-free.

A Simple Western is the Western you know well, only simplified. It is not a workaround to the existing process, a Western-like substitute, or a partial solution. It's the real thing, completely reinvented. We at ProteinSimple think that's something to get excited about!

Get your time back. Load your samples in Simon, Sally or Peggy, press start and go enjoy your new hands-free time. Come back a few hours later to fully analyzed results.
Get more consistency. People introduce variability—we arehuman after all. Simple Westerns are fully automated, so they just give you more reproducible data.
Get truly quantitative. Since blot transfer of proteins isn't needed, you can get straight to real, quantitative results.
Get more efficient. Sometimes you can only squeeze out enough sample for one experiment. Simple Westerns require a lot less protein and antibody so you have enough for those replicates.


• Learn about Simple Westerns
• Learn about Peggy
• Learn about Sally
• Learn about Simon
• Learn about NanoPro 1000
• Learn about Compass Software 21 CFR Part 11 Compliance
• Simple Western Systems Comparison Chart

Contact:

Dr. Markus Goddemeier

Sales Specialist

T: +49 (0)761 477 07 63

M: +49 (0)162 985 79 53

www.proteinsimple.com

Analytik Jena

The new generation Biometra thermal cycler – the high-performance thermal cycler for DNA amplification by PCR.

Analytik Jena


FEATURES:

  • Six different sample blocks: including a 96-well silver block as high-end variant
  • Powerful control electronics: aluminum block with superior heating and cooling rates as achieved in instruments with silver block
  • Fastest Ramping, Highest Accuracy and Intelligent Block/Well Control (RAC): high temperature uniformity and maximum reproducibility, no over- or undershooting of the programmed target temperature
  • Optional with gradient: simple optimization of new primer pairs
  • Linear Gradient Tool (LGT): exact adjustment of the gradient temperature profile
  • High Performance Smart Lid Technology (HPSL): fast heating, constant contact pressure and easy use
  • Quick Block Exchange System: easy, fast exchange of sample blocks
  • Whisper Quiet Technology: particularly quiet operation with a maximum noise level of 45 dB
  • Intuitive software: graphical programming and Easy Spreasheet Programming
  • Multi Step Programming: easy creation of PCR protocols during programming without the need to toggle between different windows
  • Advanced User Management (AUM): flexible user management with individual assignment of user rights for single users
  • User Specific Quick Start: no tedious searching of already used PCR programs due to the combination of Quick Start and Program Preview
  • Extended Self Test: automatic system diagnosis and documentation of PCR runs
  • Comfortable 7 inch color touch display
  • USB and Ethernet port
  • Protocol Wizard: Automatic creation of PCR protocols with few inputs

Contact: 

Dana Schmidt, Press

Tel: +49 36 41 77-92 81, Fax: +49 36 41 77-99 88 

presse@analytik-jena.de

www.analytik-jena.de, www.biometra.de

BD

With 100g samples, the Peptone Starter Paks allow for you to identify the correct supplements for your specific cell line faster.

BD Biosciences

BD is helping you rethink supplementation. For more than 100 years, leading pharmaceutical companies have trusted BD peptones and supplements to help improve cell culture performance with higher cell titers and yield.

The new BD Peptone Starter Paks provide samples of our most widely used peptones tailored for specific applications, including monoclonal antibodies, recombinant proteins, and vaccines, for use in both mammalian cell culture and microbial fermentation.

With 100g samples conveniently packed in one box, you can identify the correct supplements for your specific cell line faster.

Request a starter pak today and start maximizing your cell’s performance. Go to www.bdbiosciences.com/go/peptone.

Peptone Starter Paks are for evaluation use only.


Contact:

BD

7 Loveton Circle

Sparks, MD 21152

bdbiosciences.com/advbio

Analytik Jena

The BioShake series contains high-speed mixer and thermal mixer for small and very small volumes in microplates and reaction tubes and allows for the first time high precise and efficient mixing in the microliter scale for a wide range of applications.

Analytik Jena

Assays in microplates or reaction vessels can be realized fast and safe with using adjustable speed of 200 up to 3,000 rpm. The BioShake mixing-technology is obviously more robust, vibration free and needs less maintenance compared to classical mixers.

Programming the BioShake XP and BioShake iQ works via direct touch buttons. In addition two buttons for start and storage of time and mixing modes enable the instrument to run complex applications. This opens new points of view on the daily laboratory work and optimizes routine application enormously.

The short mix button allows short and fast mixing in between.

The two line LCD display guarantees simultaneous and safe reading of all programmed and measured parameters as time, mixing frequency and for BioShake iQ additional temperature.

The BioShake iQ is the high end thermal mixer of the BioShake series. In addition to the technical specifications of the model BioShake XP, the BioShake iQ comes with an very accurate heating technology. This allows highly reproducible results. The temperature range from RT to 99 °C is adjustable in 0.1 °C steps.

The temperature accuracy is ±0.1 °C, the temperature uniformity through all samples is better than ±1 °C.

The BioShake series is characterized by minor space requirement.

The BioShake series comes with a variety of standardized and specific adapter plates. The adapters allow an optimal fit for standard tubes, lysis tubes, microplates, glass vials and other sample vessels. An excellent temperature uniformity and homogeneity is guaranteed by using these adapters.

Here you get more information.

Contact: 

Dana Schmidt

Tel: +49 36 41 77-92 81 

lifescience[at]analytik-jena.de

A Thermo Fisher Scientific Brand

The GeneArt® CRISPR Nuclease mRNA is wild type Cas9 as mRNA, for genome editing using CRISPR-Cas9 technology.

Life Technologies

High-efficiency CRISPR genome-editing tools for multiplex editing

The GeneArt® CRISPR Nuclease mRNA is wild type Cas9 as mRNA, for genome editing using CRISPR-Cas9 technology. Ready-to-transfect Cas9 mRNA circumvents the need for time-consuming cloning steps required when using CRISPR vector systems. Cas9 mRNA can be co-transfected with in vitro transcribed guide RNA (IVT gRNA) or a synthetic gRNA expression cassette containing U6 promoter. The gRNA expressing cassette and IVT gRNA template can be ordered as GeneArt® CRISPR Strings™ DNA, a 500 bp DNA fragment. Following transfection, the Cas9 protein is directed by gRNA to target specific genomic locus. This system allows multiplex genome editing, where multiple target gene sequences can be edited simultaneously in a single transfection reaction with the addition of multiple gRNAs. The system is versatile and simple to use, and changing target specificity only requires a change in the design of the GeneArt® CRISPR Strings™ DNA.

For further information please click here.

3PBiopharmaceuticals

The experience acquired with one of its clients allows 3P the capability to offer this alternative technology in its services pipeline.

3PBiopharmaceuticals

The Upstream and the Technical Services teams have headed a cell free process; this is a state of the art technology that allows obtaining a specific enzyme in a non-stop fermentation process. This is possible thanks to an enzymatic biochemical reaction without any cellular mechanism interaction. 

This is an important landmark for the company in several aspects: 

  1. The successful coverage of a continuous production processes.
  2. Control of temperature during all stages to ensure stability throughout the process with adaptation of equipments and facilities to guarantee this condition
  3. The scaling-up of this technology with the singularity of maintaining constantly the temperature to guarantee the reproducibility of the process.
  4. The development of this alternative technology opens the door to those potential clients who need this type of resources to produce proteins and small molecules and sets the company in a leading position in the global biotechnology industry.

About 3PBiopharmaceuticals. 

3P is a CDMO organization that develops and manufactures biological and cellular therapy products for preclinical, clinical trials and commercial phases for other companies under GMP conditions.

Contact Information:

Edurne Gil  

3P Biopharmaceuticals Communications Manager

Tel.: + 34 984 346480

eMail: egil[at]3pbio.com

Web: www.3pbio.com

METTLER TOLEDO

METTLER TOLEDO now offers a new family of high-precision weighing platforms that provide superior accuracy and reliability in harsh industrial conditions with flexibility to be used for many applications.

METTLER TOLEDO

The new PBK9 and PFK9 Weighing Platforms provide the rugged and reliable operation customers have come to expect from METTLER TOLEDO, paired with advanced technology for high-precision weighing.

Benefits of PBK9 and PFK9 Weighing Platforms include:

  • Outstanding accuracy: The platforms are ideally suited for all weighing processes in which quality is critical and tolerances need to be minimized.
  • Reliable performance: The platforms notify the operator when recalibration or adjustments are necessary due to environmental changes.
  • Easy maintenance: Automated calibration with a built-in calibration weight and plug-in cables allow for easy maintenance.
  • Versatile and Robust: The robust load cell with integrated overload protection and IP66/IP68 ingress protection makes the platforms suitable for a variety of challenging environments including wet areas, locations with heavy dust or workplaces that need regular cleaning.

The PBK9 and PFK9 Weighing Platforms virtually eliminate the impact of environmental interferences that cause errors and result in wasted ingredients or rejected batches. Advanced Monobloc and filter technology guarantees the highest precision and reliability possible.

In addition, the PBK9 and PFK9 weighing platforms are excellent standalone solutions and they also operate well as components in applications ranging from counting and formulating to filling. PBK9 and PFK9 Weighing Platforms offer multiple options, including mild, galvanized or stainless-steel for applications in wet, dusty, harsh or hazardous environments. Nine sizes and twelve capacities from 0.6 kilograms to 3 tons with resolutions up to 750,000 divisions respectively 30,000e (legal for trade) are available. All platforms can be connected to numerous METTLER TOLEDO terminals or directly connected to a control system.

For more detail visit: www.mt.com/PBK9


Media Contact:

Melissa Braithwaite

METTLER TOLEDO

Melissa.Braithwaite[at]mt.com

614-841-7348

CANDOR

ReadyTector is an easy, quick and clear all-in-one detection solution for Western blotting.

Candor Bioscience GmbH

All-in-one solution for Western blots

The one-step solution contains all ingredients for quick immunodetection. Only a specific primary antibody has to be added. “All-in-one” stands for all ingredients in one solution as well as for all-in-one step. Blocking and binding of primary and secondary antibodies are carried out simultaneously. 

The only additional step is washing with the specific ReadyTector Wash Buffer.

ReadyTector for Western blotting is easy, quick and clear:

  • easy – very simple procedure
  • quick – very fast procedure with very quick results
  • clear – no background

The ReadyTector kit contains the all-in-one Solution and the Wash Buffer. Bottle sizes of 40 ml, 120 ml and 500 ml are available.


Contact:

Candor Bioscience GmbH

Simoniusstrasse 39

88239 Wangen, Germany

Tel.: +49(0)-7522-7952-70

Fax: +49(0)-7522-7952-729

info[at]readytector.com

www.readytector.com

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