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NEW EFS HANDBOOK PUBLISHED BY LEE PRODUCTS
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Lee Products

NEW EFS HANDBOOK PUBLISHED BY LEE PRODUCTS

Miniature component specialists LEE PRODUCTS have recently published a new EFS (Electro Fluidic Systems) technical handbook which provides a valuable resource of product information along with practical engineering reference material.

Lee Product’s three Electro-Fluidic Systems groups produce high quality miniature solenoid valves, micro-dispense valves, atomising and dispense nozzles, fixed and variable volume pumps, integrated fluidic manifolds, inert tubing and fluid control components and custom engineered designs.  These products are used in medical and scientific instrumentation, analytical / clinical chemistry, in-vitro diagnostics, drug discovery and ink jet printing applications.

This new 323 page EFS handbook includes detailed information on Lee’s wide range of solenoid valves and pumps along with their manifolds, tubing, accessories, and special products, plus useful engineering and general information.


More details and copies of the handbook are available from:

Mike Stott

Lee Products Ltd

3 High Street

Chalfont St. Peter

Gerrards Cross

Bucks, SL9 9QE

Tel: +44 (0) 1753 886664

Fax:+44 (0)1753 889588

sales@leeproducts.co.uk

www.leeproducts.co.uk

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Biological Industries

Isolate, grow, maintain and differentiate human mesenchymal stem cells from various sources with a complete, optimized culture system.

Biological Industries

Biological Industries offers a full product portfolio, including stem cell culture media, freezing media, attachment solution, cell dissociation solutions and initial differentiation kits. 

Isolation and Culture

MSC NutriStem® XF line and its supporting reagents are optimized for human mesenchymal stem cells from a variety of tissue sources and promise optimal growth and maintenance of hMSC, high proliferation rate, superior maintenance of cell characteristics, fibroblast-like morphology maintenance and long-term growth

Differentiation

MSC GoTM Osteogenic, Adipogenic and Chondrogenic  XF series offer a complete system for the evaluation and  reliable induction of hMSC from various sources into adipocytes, chondrocytes and osteoblasts/osteocytes. The kits are designed to be user friendly with all the growth factors and supplements necessary for the direct differentiation of hMSC

All products are completely free of serum and non-human derived components, hence:

  • Eliminate contagious health risks from viral agents, mycoplasma, and prions
  • Eliminate lot-to-lot variability
  • Limit immunological reactions once cells are transplanted
  • Suitable for clinical applications
  • Ensure reliable performance
  • Eliminate the drawbacks of unwanted background differentiation and interruption in the cell metabolism 


For more details please visit: www.bioind.com/mesenchymal-stem-cells

Or contact us: info@bioind.com

EPPENDORF

Whether your process includes cell culture or fermentation, autoclavable or single-use vessels, the BioFlo 320 seamlessly combines form and function in one state of the art package.

Eppendorf

A robust industrial design, intelligent sensors, Ethernet connectivity, and enhanced software capabilities are only a few of the features that set it apart from the competition. Combined with a sincere commitment to quality, the BioFlo 320 truly is the premium choice in bench-scale bioprocess control stations.

Flexible

  • Autoclavable vessels and comprehensive portfolio of BioBLU® Single-use Vessels provide process customization
  • Eppendorf exclusive packed-bed and cell lift impeller designs for continuous processes
  • Universal connections for analog or digital Mettler Toledo® ISM sensors reduce sensor complexity
  • Thermal mass flow controllers for sparge and overlay gas can be upgraded in the field

Powerful

  • Extensive working volume range of 250 mL – 40 L on a single control platform
  • High-powered direct and magnetic drive motor assemblies
  • Up to six integrated pumps capable of operating in variable speed mode
  • Industry standard Ethernet communication for multi-unit control of up to eight systems

Industrial

  • Industrial design featuring stainless steel front, back, and utility panels
  • Left- and right-handed orientations to maximize lab space efficiency
  • Hemispherical vessel nest design for minimum footprint

For more information please click here.

Contact

Eppendorf AG Bioprocess Center

Rudolf-Schulten-Str. 5

52428 Juelich

Germany

Tel: +49 2461 980-400

E-Mail: bioprocess-info@eppendorf.de

Internet: www.eppendorf.com

AMSBIO

AMSBIO announces the launch of mRNA-In™ and mRNA-In™ Neuro – a new range of high efficiency, targeted transfection reagents.

AMS Biotechnology (AMSBIO)

Offering high transfection efficiency and expression levels across a broad range of cell types, including stem cells and primary cells, mRNA-In™ is a robust and easy-to-use mRNA delivery solution proven in applications including protein expression and iPSC-reprogramming. Recognized as among the most difficult cell types to transfect, either freshly isolated or cryopreserved neurons or neural stem cells can be transfected with exceptionally low cytotoxicity using the specifically designed and optimized  mRNA-In™ Neuro reagent.

AMSBIO’s new mRNA-In™ transfection reagents require very low amounts of mRNA to achieve maximum transfection efficiency. Moreover, mRNA expression levels can be adjusted by just changing the amount of mRNA transfection thereby significantly minimizing unintended off-target immune activation. Across a wide range of cell types, mRNA-In™ reagents have been shown to produce exceptionally high transfection efficiency while maintaining optimal cell health and viability. 

Messenger RNA (mRNA) delivery has become a widely used non-viral gene delivery technique due to the significant advantages it offers. This includes almost no risk of integration into the host genome, which can lead to insertional mutagenesis and activation of oncogenes, and the ability to achieve very high transfection efficiencies nearing that of viral delivery methods. Also by contrast with DNA transfection, mRNA delivery does not enter the nucleus, rather only cytosolic delivery is required, resulting in more a rapid expression method.

Comprising a proprietary formulation of chemically defined and animal-free compounds mRNA-In™ transfection reagents are the latest addition to a growing range of nucleic acid delivery solutions from AMSBIO optimized for superior transfection efficiency and maximum cell viability.

For further information please visit www.amsbio.com/mRNA-transfection-reagent.aspx or contact AMSBIO now on +44-1235-828200 / +1-617-945-5033 or email info@amsbio.com.


Worldwide HQ:

AMS Biotechnology (AMSBIO)

184 Milton Park

Abingdon 

Oxon OX14 4SE

UK

Tel: +44-1235-828200

Fax: +44-1235-820482

Email: info@amsbio.com 

Web: www.amsbio.com

Pall

The Cadence Inline Concentrator simplifies concentrating solutions of biomolecules to an in-line, single-use, ready-to-use process.

PALL

The recirculation loop associated with tangential flow filtration (TFF) conventionally used for this process is eliminated. Pump and tube sizes are reduced, product recovery is maximized, and sensitive proteins are exposed to less shear. The Cadence Single-Use Inline Concentrator moves the product being processed through a proprietary design flow path in a pre-assembled module with all connections already in place and designed to couple to available standard tubing manifolds.

Typical applications include monoclonal antibodies, fractionated antibodies, recombinant proteins, other proteins and recombinant blood factors. The Cadence Single-Use Inline Concentrator is used to concentrate clarified bulk after fermentation, and to reduce the number or size of bags needed and increase product concentration to improve chromatography performance. 

Cost projections with BioSolve software show that, compared to conventional single-use TFF, the Cadence Single-Use Inline Concentrator provides a 31% cost of goods sold and a 66% capital investment savings per batch because of the elimination of the need for intermediate tanks, ability to use smaller chromatography columns, energy savings, and the ability to couple processes to reduce downtime.


For further information please click here.

A Thermo Fisher Scientific Brand

The GeneArt® CRISPR Nuclease mRNA is wild type Cas9 as mRNA, for genome editing using CRISPR-Cas9 technology.

Life Technologies

High-efficiency CRISPR genome-editing tools for multiplex editing

The GeneArt® CRISPR Nuclease mRNA is wild type Cas9 as mRNA, for genome editing using CRISPR-Cas9 technology. Ready-to-transfect Cas9 mRNA circumvents the need for time-consuming cloning steps required when using CRISPR vector systems. Cas9 mRNA can be co-transfected with in vitro transcribed guide RNA (IVT gRNA) or a synthetic gRNA expression cassette containing U6 promoter. The gRNA expressing cassette and IVT gRNA template can be ordered as GeneArt® CRISPR Strings™ DNA, a 500 bp DNA fragment. Following transfection, the Cas9 protein is directed by gRNA to target specific genomic locus. This system allows multiplex genome editing, where multiple target gene sequences can be edited simultaneously in a single transfection reaction with the addition of multiple gRNAs. The system is versatile and simple to use, and changing target specificity only requires a change in the design of the GeneArt® CRISPR Strings™ DNA.

For further information please click here.

DRIFTON

This is a highly advanced programmable pneumatic digital dispenser. It can store eight programmes and it can partially compensate for viscosity variation.

Drifton

The dispenser features new digital controller technology with a clear digital display for a simultaneous overview of all parameters.

The Drifton 206-DF dispenser can store eight programmes in the controller’s memory and when it is programmed, it will adjust the pneumatic pressure automatically as the liquid becomes thicker or thinner.

The dispenser can partially compensate for variation in the dispensed medium.

Remember to order an air fitting to go with this one-component dispenser.

Contact:

Drifton A/S
Avedøreholmen 84
DK-2650 Hvidovre
Tel.: +45 3679 0000
E-mail: info@drifton.dk 

Sartorius

Thanks to the intuitive user interface, operating the BIOSTAT® A is ideal for beginners, reduces operating errors and speeds up training.

Sartorius

Operation using a tablet or smartphone is a mode offered in the Advanced package and enables you to monitor and control the BIOSTAT® A on the move – in the laboratory, in the office or even at home.

Download the brochure: BIOSTAT® A - Your professional start in cell cultivation and microbial fermentation (3.5 MB) 

Contact: 

Dominic Grone

Sartorius Corporate Administration GmbH

Group Corporate Communications

Weender Landstraße 94-108

37075 Goettingen

Germany

Tel.: +49.(0)551-308.3324

Fax: +49.(0)551-308.3410

e-mail: dominic.grone@sartorius.com

Visit us: www.sartorius.com

INFORS HT

The new Bioreactor Cultivation Video Guide from INFORS HT illustrates the operational steps using the Minifors and Labfors bench-top bioreactors as examples.

INFORS HT

E-Learning: Bioreactors Made Easy!

The video instructions allow students and newcomers to fermentation to run laboratory experiments on their own. These instructions were compiled in co-operation with the University of Applied Sciences, Esslingen, (Germany) and are now available from INFORS HT.

The Cultivation Video Guide takes the user through the bioprocess step-by-step through short video clips and numerous photographs and diagrams. The guide accompanies the user through the entire bioprocess from the preparation of the pre-culture and steps to get the bioreactor ready to the actual fermentation process.

The idea was conceived by Prof. Dr. Richard Biener, University of Applied Sciences, Esslingen (Germany), since bioreactors can be damaged easily if handled inappropriately. "The operation of a bioreactor requires comprehensive training," according to Dr. Biener. "The students are excited about the instructions since complex operating steps can be shown much more comprehensibly in a video sequence". The instructions make the students more confident in the operation of the bioreactor allowing them to work more on their own and independently in the laboratory.

Dr. Burkhard Feigel (Managing Director Infors GmbH), confirms: "Younger users especially get detailed instructions without any preliminary training which allows them to perform their tasks more easily and without external help. The advisers see the special benefit in the fact that students and pupils make fewer operating errors and there are fewer defects. Basically, the instructions are very well-tried and proven in educational settings and are a type of support that is welcomed by advanced users as well."

The Cultivation Video Guide for Minifors and Labfors bioreactors is now available from INFORS HT.


Contact:

Elisabeth Konschu, Marketing Specialist

Infors AG

Rittergasse 27

4103 Bottmingen

Switzerland

Phone: +41 (0)61 425 77 00

Fax: +41 (0)61 425 77 01;

Email: e.konschu@infors-ht.com

www.infors-ht.com

SARTORIUS

Sartorius Stedim Biotech presents the new system FlexAct® that enables you to custom- configure single-use solutions for entire biomanufacturing steps.

Sartorius Stedim Biotech

FlexAct® is a new system that enables you to custom- configure single-use solutions for entire biomanufacturing steps. The FlexAct® system consists of the central opera- ting module that offers the widest variety of configuration options so you can take complete control of practically any steps in upstream and downstream processing.

Sartorius Stedim Biotech presents the FlexAct® BP for buffer preparation. Next in line are media preparation (MP), cell harvest (CH), UF | DF crossflow (UD), virus removal (Vr), virus inactivation (VI), polishing (PO), form | fill (FF) and form | transfer (FT).

The core of FlexAct®, the central operating module (COM), has been designed to be used in any application. This means you can quickly reconfigure FlexAct® in just a few easy steps. For example, take the FlexAct® BP for buffer preparation and effortlessly convert it into FlexAct® VR for virus removal.

And it goes without saying that the technologies and products used in FlexAct® are scalable. This makes FlexAct® a future-proof system in every respect; one that gives you the greatest possible flexibility.


Contact:

Dominic Grone

Group Corporate Communications

Sartorius AG

Goettingen

Phone:+49.(0)551.308.3324

email: dominic.grone@sartorius.com

web: www.sartorius.com

Brady

From basic label design and printing to advanced import and editing options, LabelMark software improves the label-making experience for the electrical, industrial, aerospace, laboratory and telecom industries.

BRADY

New LabelMark™ 6 software takes the hassle out of designing and printing labels. With an improved user interface and app-based navigation combined with Brady’s proven interactive label creation and single-click importing and serialization, you have high performance label printing that has never been easier.

Label Printing with an improved user interface:

  • Easy-to-use apps for creating wire harness, control panel and laboratory labels
  • Insert and edit AutoCAD layers, area of interests or entire files
  • Automatically repeat text on multiple lines of a label with LabelMark wire marker tool
  • Multi-label view for true representation of label formats
  • Adjust each individual label’s length in your print file

Data Management:

  • Quickly import data onto a label from an external data source
  • One-step serialization of data
  • “Check error” function to locate any import errors in prior to printing

Label Printing:

  • Assign label materials to a specific printer for dedicated printing
  • Manage multiple files in a single job by grouping wire markers, push buttons, rating plates, and terminal block labels into one job file
  • Bi-directional communication with the IP, BMP®41, BMP®51,BMP®53, BMP®71 and BBP®33 printer series for automatic label format loading

For more information, visit BradyID.com/labelmark

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No liability assumed, Date: 01.04.2015

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