18.01.2013 - British vaccine specialist PsiOxus Therapeutics Ltd. has baged a US$3.3m development contract from US Defense Threat Reduction Agency.
Under the terms of the agreement, the Oxford-based company will develop biodefence vaccine adjuvants. Using its PolyMAP platform, the company’s research will be aimed at improving safety and efficacy of two existing vaccine candidates: the recombinant protective antigen (rPA) against Anthrax and the Venezuelan Equine Encephalopathy Virus (VEEV). A monoclonal antibody targeting Anthrax has been recently approved by the US FDA.
The contract will support work over a three-year period in the US, as well as in the company’s new laboratory in Oxford, which has been designed and equipped as a category two laboratory for the handling of live viruses.
PsiOxus Therapeutics’ PolyMAP technology links polymers to synthetic adjuvants that activate specific sets of Toll-like receptors (TRLs), which significantly boosts the effectiveness of vaccines in a controlled manner.