23.01.2013 - Merck-Serono spin-out Prexton Therapeutics has secured an exclusive licence option on a Parkinson candidate of Domain Therapeutics.
The Strasbourg-based company's metabotropic glutamate receptor 4 (mGluR4) Positive Allosteric Modulator (PAM) was previously developed through a licensing and collaboration agreement signed between Domain and Merck Serono in January 2011. Prexton was spun out following Merck Serono restructuring, taking on the mother company's R&D portfolio in the field of Parkinson's disease.
Under the terms of the agreement signed between Domain and Prexton, Prexton will benefit from an exclusive license option to progress two mGluR4 PAM drug candidates into clinical development. mGluR4 is a glutamate receptor, member of the G-Protein Coupled Receptor (GPCR) family and is believed to be a potential therapeutic target for Parkinson’s disease. Allosteric modulation of mGluR4 receptors is thought to exert regulatory activity onglutamate-mediated neurotransmission
29.08.2014 Just a week ago, Glaxosmithkline defused the WHO’s claim that an Ebola vaccine could be ready by 2015. Now, the British company’s own candidate vaccine is to be rushed to human trials with the help of funding from an international consortium.
24.08.2014 Germany's Morphosys is licensing a preclinical bi-specific antibody for the treatment of prostate cancer from Emergent Biosolutions. The US developer will rake in up to €138m for the commercialisation rights to the compound.
20.08.2014 Biopharmaceutical contract manufacturer Fujifilm Diosynth Biotechnologies is expanding its cell culture manufacturing capacity further with a new 2,000l single-use bioreactor at the company’s site in Billingham, UK.
08.08.2014 Boehringer Ingelheim is walking away from Swedish Orexo's prostaglandin inhibition project OX-MPI. Germany's largest researching pharmaceutical company had been responsible for the project's research and development since 2005.