News

Otsuka snags Lu AE58054
Enlarge image

BusinessDenmark

Otsuka snags Lu AE58054

28.03.2013 - Japanese Otsuka and Danish Lundbeck have inked a US$825m co-development and co-marketing deal in Alzheimer's disease.

Under the terms of the agreement, the Copenhagen-based neurology specialist will grant Otsuka (Tokyo) co-development and co-commercialisation rights to its selective 5-HT6-receptor antagonist LU AE58054 in the US, Canada, East Asia, Japan, and major European pharma markets.

The Japanese company will pay US$150m upfront. Both companies will share the sales, development, and commercialisation costs. Lundbeck is also entitled to up to US$675m in milestones.  

A pivotal clinical programme with Lu AE58054 enroling more than 2,500 patients with mild-to-moderate Alzheimer's disease is planned to be initiated later this year. Lu AE58054 will be tested as adjunct treatment to donepezil. Last May, Lundbeck reported that Lu AE58054 had met its primary endpoint in a 24-week clinical Phase II trial in 278 patients in the same setting as the confirmatory Phase III study.

© eurobiotechnews.eu/tg

http://www.european-biotechnology-news.com/news/news/2013-01/otsuka-snags-lundbecks-lu-ae58054.html

2014EU

19.12.2014 We took a look back at 2014: which European Biotechnology News stories topped the charts this year?

R&DEUBelgium

18.12.2014 IMI has launched a €115m call for proposals involving a project in collaboration with the Bill and Melinda Gates Foundation to improve vaccines against whopping cough in children.

PoliticsEUPolandItalySpainUK

16.12.2014 Two consortia combined of 144 European companies, research institutes and universities have been selected for funding by the EIT in the areas of health and raw materials. Both clusters are set to acquire €1.1bn over the next seven years.

M&ALuxembourg

11.12.2014 Luxembourg bio-analytical testing company Eurofins Scientific has signed an agreement to acquire Boston Heart Diagnostics Corp. for an initial €112m.

StudySwitzerlandEU

10.12.2014 When it comes to the biggest investors in Research and Development (R&D) Swiss pharma top dogs Novartis and Roche have defended their positioning among the top ten companies worldwide – according to a recently published EU study.

FinancingUKSpain

09.12.2014 British drug delivery specialist Midatech Pharma plc floated on the London stock market. It is the third biotech IPO on the AIM market this year.

CooperationAustria

05.12.2014 Austrian contract research company VTU has entered into a development and commercialisation agreement with US company RCT. The partners want to combine both companies' Pichia pastoris protein production technologies under VTU's roof.

FinancingDenmark

03.12.2014 Danish biotech pharma Ascendis has successfully completed a €48m Series D financing round. The funding is expected to support its late-stage clinical trials to push its lead drug into Phase III trials.

Events

All Events

Current issue

All issues

Product of the week

Products