News

Enlarge image

FundingBelgium

Fresh funds for Galapagos

31.01.2013 - Belgian Galapagos NV has secured €2.5m from Flemish IWT to screen for new compounds to treat inflammatory bowel disease (IBD).

The goal of the 2.5-year project is to find new compounds  against IBD, a chronic, uncontrolled inflammation of the intestinal mucosa such as Crohn's disease and ulcerative colitis. The Mechelen-based company already runs a Phase I programme termed GLPG0974 that reduces migration of neutrophils by targeting GPR43 (FFA2).

The purpose of the IWT-funded program is to improve its understanding of the roles of GPR43 and two other undisclosed targets in the pathobiology of chronic inflammatory disorders. Galapagos will collaborate in this project with Professor Dr Paul Rutgeerts and Professor Dr Séverine Vermeire from the Catholic University of Leuven, and the research group of Professor Dr Martine De Vos at Ghent University.  

The 2010 winner of the European Biotechnica Award has also partnered and unpartnered programmes in rheumatoid arthritis (RA). "After RA, IBD is the second autoimmune disease focus for Galapagos. With this grant we will gain a better understanding of the cause of IBD, and this will contribute to the search for better medicines," said Piet Wigerinck, CSO of Galapagos. The current understanding of the pathogenesis of IBD is limited. The characteristic inflammatory response begins with infiltration of neutrophils and macrophages, which release chemokines and cytokines. These in turn exacerbate the dysfunctional immune response and activate cellular and humoral responses in the gut mucosa.

© eurobiotechnews.eu/tg 

http://www.european-biotechnology-news.com/news/news/2013-01/fresh-funds-for-galapagos.html

Clinical ResearchFrancePortugalEU

05.02.2016 It is not yet clear why a man died during a first-in-man clinical trial in January. A preliminary report found several “major shortcomings” by responsible CRO Biotrial. However, all regulations were complied with.

M&ASwitzerland

04.02.2016 After having dodged multiple takeover attempts by Monsanto last year, agrobusiness giant Syngenta has now agreed to be acquired by chemical corporation ChemChina. The Swiss company also announced plans to go public within a few years.

FinancingEUUKBelgium

01.02.2016 Newly formed Medicxi Ventures, a life sciences-dedicated VC firm based in London, Geneva and Jersey, has closed a €210m investment fund to reinvest in European early-stage assets.

ResearchUKEU

01.02.2016 Altering human DNA with the efficient gene editing method CRISPR/Cas9, especially germline modifications, was long considered a taboo. Now, however, UK scientists have received official approval to tinker with embryo DNA.

M&ASwedenIceland

28.01.2016 Swedish infectious disease specialist Enzymatica has bagged Icelandic company Zymetech, who produces the patent-protected enzyme used in Enzymatica’s own common cold blocker ColdZyme.

R&DUK

27.01.2016 Three UK universities have teamed up with three pharma companies to create the Apollo Therapeutics Fund. With the tech transfer fund, the consortium aims to develop scientific research into medicines.

Clinical TrialsGermany

25.01.2016 Affimed means to put a promising drug combination to the test. With support from MSD, the German biopharma will carry out clinical trials for an immunotherapy combining treatments of both companies.

AMREU

21.01.2016 Stop squandering antibiotics and make research profitable again: at the World Economic Forum in Swiss Davos, 83 pharmaceutical companies have called for a unified approach towards the threat of antimicrobial resistance.

M&AFinland

19.01.2016 Biotie Therapies has long been expanding its business in the US. Now, the Finnish company is set to be taken over by US company Acorda Therapeutics, which is paying €321m for the shares.

Drug AssessmentPortugalFrance

18.01.2016 A Phase I clinical trial for a drug developed by Portuguese pharma company Bial has ended in disaster. One man died, five others may have irreversible neurological damage.

Events

All Events

Current issue

All issues

Product of the week

Products

Stock list

All quotes

TOP

  • SAREUM HOLDINGS (UK)0.28 GBP12.00%
  • IXICO (UK)35.50 GBP4.41%
  • SUMMIT (UK)4.03 GBP3.87%

FLOP

  • SWEDISH ORPHAN BIOVITRUM (S)12.45 USD-23.38%
  • BIOTIE THERAPEUTICS (FI)0.14 EUR-22.22%
  • THERAMETRICS (CH)0.04 CHF-20.00%

TOP

  • VERONA PHARMA (UK)3.25 GBP22.6%
  • IXICO (UK)35.50 GBP20.3%
  • SAREUM HOLDINGS (UK)0.28 GBP16.7%

FLOP

  • BIONOR PHARMA (N)0.80 NOK-48.7%
  • PROTHENA PLC (IE)30.94 USD-42.6%
  • PLETHORA (UK)2.62 GBP-36.4%

TOP

  • CHRONTECH PHARMA (S)0.34 SEK3300.0%
  • KARO BIO (S)24.00 SEK2826.8%
  • 4SC (D)3.04 EUR257.6%

FLOP

  • BIOTEST (D)11.91 EUR-87.3%
  • NEUROVIVE PHARMACEUTICAL AB (S)8.70 SEK-85.3%
  • EVOCUTIS (UK)0.08 GBP-71.4%

No liability assumed, Date: 09.02.2016