News

Study claims GMO cancer risk
Enlarge image

PolicyEUUKFranceSpain

Study claims GMO cancer risk

21.09.2012 - Researchers from the organisation Criigen have published a GMO feeding study suggesting a cancer risk in mice. Critics say the study design was not appropriate.

In the peer reviewed journal Food and Chemical Toxicology a team headed by Criigen president Gilles-Eric Seralini report that lab mice fed with Monsanto’s GM maize NK603 or with the herbicide Glyphosate developed faster tumours than control mice. While treated female rats died 2-3 fold more frequently than controls, male rats which received the GMO or herbicide diet over 2 years developed tumours, which were up to 4 times larger than in control mice and occurred earlier in their life cycle, accompanied by kidney defects in both sexes.

However, critics questioned the credibility and reliability of the data. "The methods, stats and reporting of results are all well below the standard I would expect in a rigorous study – to be honest I am surprised it was accepted for publication“, stated Prof. Dr. David Spiegelhalter from University of Cambridge, UK, explaining that there was no full data set, no relevant number of animals involved to demonstrate statistical significance and no dose-dependent effect confirming the conclusions of the study authors. Prof. Dr. Maurice Moloney, chief of Rothamsted Research, pointed to the fact that the rat species used by the French researchers is extremely susceptible to developing spontaneous cancers, with up to 86% in wild-type males and 72% in normal females. According to Dr. Wendy Harwood, John Innes Centre, „without access to the full data, we can only say that these results cannot be interpreted as showing that GM technology itself is dangerous.“ Some researchers also criticised that it was not good scientific practice to give the data to the press before making them public to the scientific community. Others such as Prof. Dr. Jose Miquel Mulet from University of Valencia presumed the study was politically motivated: The reports of Criigen are put forward by the French authorities as justification to maintaining bans on cultivating GMOs,“he stressed. French Prime Minister Jean-Marc Ayrault stated in Paris: "The government is keeping its moratorium on the cultivation of GMO seeds currently authorised in the European Union." 

A spokesman of the European Food watchdog EFSA said it will consider the paper’s relevance (http://www.efsa.europa.eu/en/press/news/120919b.htm). The study appears as a direct attack on the EFSA’s methods. However, recently, an independent study carried out by Ernst & Young confirmed the agency’s assessments had excellent scientific quality.  

Since the foundation of Criigen in 2001, its researchers have questioned the design of animal studies used to assess GMO safety. The organisation is financed through contract research . Although its researchers carry out contract studies for Greenpeace and Carrefour, the large French food retailer which claims its products to be GM-free, its researchers say the organisation is independent.

© eurobiotechnews.eu/tg

http://www.european-biotechnology-news.com/news/news/2012-03/study-claims-gmo-cancer-risk.html

R&DUKIreland

12.02.2016 The promise of the microbiome as the basis of new treatments has caught the attention of many. Now, UK biotherapeutics maker 4D pharma plc has padded its microbiome pipeline with the acquisition of Irish Tucana Health.

CommercialisationEU

10.02.2016 In future, meds will come in packages sporting a unique barcode and an anti-tampering device. These measures are part of the EU’s new regulation to safeguard against falsified medicines.

Clinical ResearchFrancePortugalEU

05.02.2016 It is not yet clear why a man died during a first-in-man clinical trial in January. A preliminary report found several “major shortcomings” by responsible CRO Biotrial. However, all regulations were complied with.

M&ASwitzerland

04.02.2016 After having dodged multiple takeover attempts by Monsanto last year, agrobusiness giant Syngenta has now agreed to be acquired by chemical corporation ChemChina. The Swiss company also announced plans to go public within a few years.

FinancingEUUKBelgium

01.02.2016 Newly formed Medicxi Ventures, a life sciences-dedicated VC firm based in London, Geneva and Jersey, has closed a €210m investment fund to reinvest in European early-stage assets.

ResearchUKEU

01.02.2016 Altering human DNA with the efficient gene editing method CRISPR/Cas9, especially germline modifications, was long considered a taboo. Now, however, UK scientists have received official approval to tinker with embryo DNA.

M&ASwedenIceland

28.01.2016 Swedish infectious disease specialist Enzymatica has bagged Icelandic company Zymetech, who produces the patent-protected enzyme used in Enzymatica’s own common cold blocker ColdZyme.

R&DUK

27.01.2016 Three UK universities have teamed up with three pharma companies to create the Apollo Therapeutics Fund. With the tech transfer fund, the consortium aims to develop scientific research into medicines.

Clinical TrialsGermany

25.01.2016 Affimed means to put a promising drug combination to the test. With support from MSD, the German biopharma will carry out clinical trials for an immunotherapy combining treatments of both companies.

AMREU

21.01.2016 Stop squandering antibiotics and make research profitable again: at the World Economic Forum in Swiss Davos, 83 pharmaceutical companies have called for a unified approach towards the threat of antimicrobial resistance.

Quick news provided by GlobeNewswire

View more stock news

Events

All Events

Current issue

All issues

Product of the week

Products

Stock list

All quotes

TOP

  • PAION (D)1.77 EUR63.89%
  • 4SC (D)2.95 EUR11.32%
  • BIONOR PHARMA (N)0.86 NOK8.86%

FLOP

  • STENTYS (F)2.83 EUR-26.30%
  • BIOTIE THERAPEUTICS (FI)0.14 EUR-22.22%
  • KARO BIO (S)24.60 SEK-16.04%

TOP

  • VERONA PHARMA (UK)3.40 GBP25.9%
  • IXICO (UK)35.75 GBP21.2%
  • SERODUS (N)2.71 NOK15.8%

FLOP

  • BIONOR PHARMA (N)0.86 NOK-47.2%
  • STENTYS (F)2.83 EUR-44.3%
  • MOLMED (I)0.24 EUR-35.1%

TOP

  • CHRONTECH PHARMA (S)0.34 SEK3300.0%
  • KARO BIO (S)24.60 SEK3053.8%
  • 4SC (D)2.95 EUR243.0%

FLOP

  • NEUROVIVE PHARMACEUTICAL AB (S)8.65 SEK-86.0%
  • BIOTEST (D)13.79 EUR-85.3%
  • EVOCUTIS (UK)0.08 GBP-69.2%

No liability assumed, Date: 13.02.2016