08.08.2012 - Pfizer, Johnson & Johnson and Elan will end the development of bapineuzumab. The antibody was thought to become a treatment for Alzheimer's disease with hundreds of millions in sale.
The decision came after the antibody targeting amyloid beta did not meet the co-primary endpoints of change in cognitive and functional performance in a phase III study in patients lacking a mutation in the apolipoprotein E epsilon. The trial was led by J&J's research affiliate Janssen Cilag. Some experts said the result came as no surprise as the window of success was very small. Nevertheless, Bapineuzumab is one of the most advanced antibodies targeting amyloid beta. For Elan's future, the study failure could have a large effect. The company was responsible to pay for 49,9% of the trial costs. That leads to a US-$117.3m non-cash impairment charge in the third quarter of 2012. Elan shares fell more than 12%. Analysts speculated that the the success of bapineuzumab could influence a potential sale of the company, noting that Elan's partner Biogen Idec could step in at the right price.
17.04.2014 The European Parliament has given green light to the second Innovative Medicines Initiative with the aim to advance pharmacological research and development, particularly in areas of unmet medical need.
11.04.2014 There is no evidence that neuraminidase inhibitors Tamiflu and Relenza prevent complications of influenza or reduce hospital admissions. In addition, it is unclear whether they can stop the spread of influenza in case of outbreaks, says a report by the Cochrane Collaboration.
09.04.2014 Roche is extending its involvement in the area of point-of-care diagnostics by taking over US company Iquum. In the field of epigenetics, the Swiss pharma company has started a cooperation with the Spanish company Oryzon.
08.04.2014 The Swiss Biotech Report 2014 presented in Zurich sees an encouraging upturn in the country's biotech scene. However, the acceptance of the mass immigration initiative poses a significant threat.
The LiposoFast-Basic produces unilamellar liposomes by the manual extrusion of a multilamellar liposome suspension through a polycarbonate membrane of defined pore size, using gas-tight, glass syringes. more