08.08.2012 - Pfizer, Johnson & Johnson and Elan will end the development of bapineuzumab. The antibody was thought to become a treatment for Alzheimer's disease with hundreds of millions in sale.
The decision came after the antibody targeting amyloid beta did not meet the co-primary endpoints of change in cognitive and functional performance in a phase III study in patients lacking a mutation in the apolipoprotein E epsilon. The trial was led by J&J's research affiliate Janssen Cilag. Some experts said the result came as no surprise as the window of success was very small. Nevertheless, Bapineuzumab is one of the most advanced antibodies targeting amyloid beta. For Elan's future, the study failure could have a large effect. The company was responsible to pay for 49,9% of the trial costs. That leads to a US-$117.3m non-cash impairment charge in the third quarter of 2012. Elan shares fell more than 12%. Analysts speculated that the the success of bapineuzumab could influence a potential sale of the company, noting that Elan's partner Biogen Idec could step in at the right price.
27.04.2016 More revenue, more jobs, more financing, more R&D expenditure – all signs point towards sustainable growth in the German biotech sector. These are the results of the most recent company survey 2016, published by biotechnologie.de. The report was once again conducted alongside the biotech standards defined by the organisation for economic cooperation and development (OECD).
21.04.2016 An expert panel’s final report on the fatal drug trial earlier this year in France states that the death of one of the participants was most likely caused by the drug’s toxicity and not by any violation of the rules.
21.04.2016 For up to US$685m (€606m), Dutch ArgenX has outlicensed its human antibody programme ARGX-115 to AbbVie. The pre-clinical immuno-oncology candidate targets a protein believed to contribute to immunosuppressive effects of T-cells.
19.04.2016 British drug developer Heptares Therapeutics and mAb maker Kymab Ltd have partnered up in yet another immuno-oncology collaboration. The companies plan to discover antibody meds targeting a superfamily of receptors.
15.04.2016 Not every company is put off by the current stock market climate. Swiss biopharma company GeNeuro has gone public at Euronext Paris, raising €33m in the process. Others, meanwhile, have to find different ways to raise money.
13.04.2016 Despite political disturbances, 2015 was a good year for the biotech scene in Switzerland. Net sales increased by 5.1% to CHF5,133m and 400 additional people found jobs in the sector. As usual, the new numbers were presented at the annual Swiss Biotech Day – which set new records as well.
12.04.2016 German-Dutch life science investment specialist Forbion Capital Partners has raised more than €180m for its venture capital fund Forbion Capital Fund III. Once more the money will primarily go to European start-ups.
08.04.2016 Do you win by being innovative?, was the question asked at this year’s DIA Euromeeting in Hamburg. In a relaxed and cooperative atmosphere, regulators, physicians and patients had ample opportunity to interact with the healthcare industry.
07.04.2016 Pfizer and Allergan have called off their merger, cancelling plans to relocate the US pharma giant to Ireland to avoid US taxation. The US government has put a spoke in Pfizer’s wheels - an unfair move, Allergan says.