11.04.2012 - Spanish drug developer will focus internal resources on its late-stage compounds.
Madrid – Spanish drug developer PharmaMar SA has quit the further development of its Phase II drug candidate Irvalec due to financial reasons. According to the company, the marine-derived cyclic peptide has shown notable activity in a trial to treat gastroesophageal cancer specifically in large cell undifferentiated carcinomas of the esophagus. However, this subtype is relatively rare and represents only 1% of all gastroesophageal cancers. The company, a member of listed Zeltia Group, will focus its resources on other compounds like Yondelis and Aplidin. Yondelis is approved outside the US to treat advanced or metastatic soft tissue sarcoma and relapsed platinum-sensitive ovarian cancers. The conotoxin has additionally been tested as first-line therapy for this indication. Aplidin is in phase III to treat multiple myeloma and in phase II for T-cell lymphoma.
05.02.2016 It is not yet clear why a man died during a first-in-man clinical trial in January. However, a preliminary report found several “major shortcomings” by responsible CRO Biotrial. However, all regulations were complied with.
04.02.2016 After having dodged multiple takeover attempts by Monsanto last year, agrobusiness giant Syngenta has now agreed to be acquired by chemical corporation ChemChina. The Swiss company also announced plans to go public within a few years.
01.02.2016 Altering human DNA with the efficient gene editing method CRISPR/Cas9, especially germline modifications, was long considered a taboo. Now, however, UK scientists have received official approval to tinker with embryo DNA.
27.01.2016 Three UK universities have teamed up with three pharma companies to create the Apollo Therapeutics Fund. With the tech transfer fund, the consortium aims to develop scientific research into medicines.
25.01.2016 Affimed means to put a promising drug combination to the test. With support from MSD, the German biopharma will carry out clinical trials for an immunotherapy combining treatments of both companies.
21.01.2016 Stop squandering antibiotics and make research profitable again: at the World Economic Forum in Swiss Davos, 83 pharmaceutical companies have called for a unified approach towards the threat of antimicrobial resistance.