Politics / Law

Progress in cutting animal testing

14.07.2009

Parma – European food watchdog EFSA has summarised the current capabilities of in vitro tests to reduce, replace and refine (“3Rs”) animal testing in food safety assessment. Its 77-page report tabled in June concluded that “at present, the tests cannot provide the information that can be derived from in vivo tests.” But it also recommends stimulating their use and development, with full replacement of animal tests as a long-term goal. According to the authority’s scientific committee, the most progress has been made in the area of eye irritation testing, where four in vitro methods allow classification of severe eye irritants. In genotoxicity testing, initial tests are often carried out in vitro, but currently need to be confirmed by in vivo methods. In the area of skin corrosion testing, in vitro-tests are established by law. A skin irritation in vitro test should receive OECD approval soon. Important areas where in vitro testing would be required but are currently not available include toxicokinetics assessment, acute toxicity testing, skin sensitation testing and tox testing with complex endpoints such as repeated dose toxicity, ecotoxicity, and reproduction/development toxicity testing.

Politics / Law

23.03.2012

Brussels/Strasbourg – Health claims are set to be drastically limited in the EU. On Wednesday 21 March the Environment Committee of the European Parliament confirmed a proposal of the European Commission to prohibit 1,600 health...

Politics / Law

15.03.2012

Parma/Stockholm – Foodborne bacteria such as Salmonella and Campylobacter are becoming more and more resistant to antimicrobial drugs, according to a joint report published by the European food watchdog EFSA and the European...

BioFunding

09.03.2012

In mid-February, scientists and entrepreneurs from nine EU countries met at the Center for Genomic Regulation (CRG) in Barcelona to launch the 4DCellFate project. Positioned within the FP7 Programme, the consortium will receive...

BioFunding

09.03.2012

Brussels – The EU’s Innovative Medicines Initiative (IMI) will establish the European Lead Factory, an EU-wide public-private partnership aiming to facilitate drug discovery efforts. The Lead Factory will comprise a...

Editorial

07.03.2012

T    he societal and economic challenges facing Europe and the world are complex and interconnected. The Bioeconomy Strategy and Action Plan “Innovating for Sustainable Growth: a Bioeconomy for Europe”, which was adopted by the...

Tech Review

07.03.2012

Intellectual Property (IP) is without question one of the most vital aspects of any bio­tech venture, a key and undisputed factor for success. However, most bio­tech companies are still incapable of unlocking the value of their...

Clinical Trial

07.03.2012

Schlieren – Swiss Cytos Biotechnology Ltd. has been authorised to restructure a convertible bond by Canton of Zurich authorities. The company does not have enough cash to pay it back. Negotiations with bond holders failed in a...

Clinical Trial

06.03.2012

Munich – German 4SC AG jumped 39% to €2.05/share after oncology drug candidate resminostat met the primary endpoint of at least a 20% progression-free survival rate in a Phase II trial to treat patients with hepatocellular...

Editorial

06.03.2012

The start of 2012 witnessed the tides turning in favour of small and mid-cap names in the European Life Sciences sector. Major global biotechnology indices like the NBI, BTK, and BIOTK are up over 15% year to date. The pace of...

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