Clinical Trial

Boehringer Ingelheim takes Evotec’s painkiller into clinic

01.06.2011

Hamburg/Ingelheim: Evotec AG’s second oral compound against neuropathic pain has reached clinical development stage. The progress triggered a EUR 2 million milestone from Boehringer Ingelheim that will pay all clinical development and commercialisation costs of compounds co-developed within the ongoing strategic alliance the companies initially signed in 2004. Neuropathic pain, which is estimated to affect up to 8% of the world’s population, is a type of pain caused by damage to or dysfunction of the nervous system. This March, Boehringer Ingelheim prematurately terminated a first-in-man dose escalation study (NCT01145014) of its compound BI 660848, intended to be developed in neuropathic pain, due to „new embryotoxicology data but not for safety reasons“. The transition of the new back-up compound into clinical stage triggered the 13th milestone for Evotec within the alliance with Boehringer Ingelheim that includes several unnamed compounds „working on multiple high priority targets across key therapeutic areas“. Following the end of the collaboration with Roche on EVT 101, Evotec which increased its Q1/2011 revenues by more than 50% (EUR15.1m) compared to Q1/2010, requires a positive newsflow.

Politics / Law

23.03.2012

Brussels/Strasbourg – Health claims are set to be drastically limited in the EU. On Wednesday 21 March the Environment Committee of the European Parliament confirmed a proposal of the European Commission to prohibit 1,600 health...

Politics / Law

15.03.2012

Parma/Stockholm – Foodborne bacteria such as Salmonella and Campylobacter are becoming more and more resistant to antimicrobial drugs, according to a joint report published by the European food watchdog EFSA and the European...

BioFunding

09.03.2012

In mid-February, scientists and entrepreneurs from nine EU countries met at the Center for Genomic Regulation (CRG) in Barcelona to launch the 4DCellFate project. Positioned within the FP7 Programme, the consortium will receive...

BioFunding

09.03.2012

Brussels – The EU’s Innovative Medicines Initiative (IMI) will establish the European Lead Factory, an EU-wide public-private partnership aiming to facilitate drug discovery efforts. The Lead Factory will comprise a...

Editorial

07.03.2012

T    he societal and economic challenges facing Europe and the world are complex and interconnected. The Bioeconomy Strategy and Action Plan “Innovating for Sustainable Growth: a Bioeconomy for Europe”, which was adopted by the...

Tech Review

07.03.2012

Intellectual Property (IP) is without question one of the most vital aspects of any bio­tech venture, a key and undisputed factor for success. However, most bio­tech companies are still incapable of unlocking the value of their...

Clinical Trial

07.03.2012

Schlieren – Swiss Cytos Biotechnology Ltd. has been authorised to restructure a convertible bond by Canton of Zurich authorities. The company does not have enough cash to pay it back. Negotiations with bond holders failed in a...

Clinical Trial

06.03.2012

Munich – German 4SC AG jumped 39% to €2.05/share after oncology drug candidate resminostat met the primary endpoint of at least a 20% progression-free survival rate in a Phase II trial to treat patients with hepatocellular...

Editorial

06.03.2012

The start of 2012 witnessed the tides turning in favour of small and mid-cap names in the European Life Sciences sector. Major global biotechnology indices like the NBI, BTK, and BIOTK are up over 15% year to date. The pace of...

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