SpainSpain

Spanish start up to develop therapeutic HPV vaccine

18.06.2008

A Madrid – About 70% of all women will become infected with papilloma viruses (HPV) at least once in their lifetime. Now, the Spanish vaccine specialist Chimera Pharma SL (Madrid) has signed an exclusive licensing and cooperation agreement with the German Cancer Research Centre (DKFZ) in Heidelberg. Under the agreement, the two partners will develop, a therapeutic vaccine against cervical cancer to prevent women who are already infected with HPV from developing cancer, and to eradicate existing cancer prestages. Chimera has got exclusive world-wide rights to commercialise thevaccine.

Huge market promise

The market for a vaccine that kills the cancer-causing virus subtypes seems to be extremely promising. Sanofi-Pasteur MSD, which licensed IP from Chimera’s German cooperation partners under Prof. Harald zur Hausen and Dr. Angel Cid-Arregui, has made EUR1.3bn revenues with the prophylactic HPV vaccine Gardasil® since its market launch in June 2006.
Together with our Spanish partners, we will develop a protein vaccine against HPV16 and HPV18, which are linked to cervical cancer,” Cid-Arregui told EuroBiotechNews. The vaccine will be based on fusion proteins of three HPV envelope protein domains with the HBSAg envelope protein of the Hepatitis-B virus, which forms empty immunogenic virus envelopes. In addition to this, the virus shells can transport further proteins that stimulate the immune system.
“Similar to our patented (US-PTO 7,201,908) vaccine candidate, we have demonstrated the preclinical efficacy of our new compound,” says Cid-Arregui. The young Spanish company – part of Madrid-based Grupo Bionostra – is currently beginning toxicological studies, and is planning to establish GMP production by February, and to file an application for clinical development by summer 2009. Like many biotech companies that develop compounds to Phase 2 for outlicensing to big pharma, Chimera currently does not have the resources for full clinical development. Thus, at the moment outlicencing to a big pharma company seems the most probable exit

SpainSpain

08.03.2012

Granada-based Integromics S.L. has teamed up with the Galician Foundation of Genomic Medicine (FPGMX) in Santiago de Compostela to secure a €1m EU grant from the European Regional Development Fund and the Spanish government. With...

SpainSpain

08.03.2012

Oryzon Genomics S.A (Barcelona) is entering preclinical testing with a first-in-class bispecific LSD1/MAO-B inhibitor. In addition to the classic target MAO-B, the drug also blocks histone demethylase LSD1, an epigenetic histone...

SpainSpain

06.03.2012

Granada-based nLife Therapeutics S.L. has raised €5m in total from two venture capitalists. Through Caixa Capital Risc and Caixa Capital Biomed, La Caixa invested €2.5m. The same amount has been placed by Invercaria via its...

SpainSpain

05.03.2012

Ordesa Laboratories has filed a patent for a novel Bifidobacterium strain isolated from infant feces. It has the capacity to combat rotavirus, says a study (Appl. Environ. Microbiol., doi:10.1128/AEM.05548).

SpainSpain

19.12.2011

Madrid – Researchers from Spain and the US have discovered an Ebola-like filovirus in bats in northern Spain. The first known filovirus native to Europe was reported in a study published in the journal PLOS Pathogens...

SpainSpain

15.12.2011

Barcelona - South western Europe gets a new R&D unit in the field of biomolecules. Kymos Pharma, a contract researcher based in Barcelona, has signed an agreement with the French biotechnology group Ipsen to create a R&D group...

SpainSpain

12.12.2011

Barcelona/Saffron Walden – Almirall S.A. and BioFocus announced that they have entered into a collaboration agreement to identify new compounds against key targets in projects aimed at the treatment of respiratory and...

SpainSpain

03.12.2011

Madrid/Abu Dhabi – Spanish biotechs are seeking collaborations with firms in the United Arab Emirates. At the end of November, Grupo Zeltia and 14 other Spanish companies presented their research at the forum “Innovation,...

SpainSpain

01.10.2011

Madrid – The Spanish Minister of Innovation and Science Cristina Garmendia has responded to reports about Roche’s­ delivery stop in Greece and pessimistic expectations for Spain. In Sept­ember, she stressed that the atmosphere...

Displaying results 1 to 10 out of 181

1-10 Next >

© 2007-2015 BIOCOM

http://www.european-biotechnology-news.com/news/messages-archive/archive-spain/article/spanish-start-up-to-develop-therapeutic-hpv-vaccine.html

Video

All videos

Product of the week

Products

WhitePaper

LentiKat’s offers an unusual investment opportunity

LentiKat’s owns, manufactures and distributes a patented immobilization into lentil-shaped Lentikats Biocatalysts. The unique lentil-like shape of the Lentikats Biocatalyst ensures unlimited diffusion of substrate(s) into any part of the matrix, while still retaining a convenient size for easy separation from the reaction medium. They find application in the Pharma & Food industry (including bio-based chemicals), Wastewater treatment as well as Biofuels. more...

Events

All Events

Partner-Events

München

BioVaria 2015

Job Advert

Sales Manager

celares GmbH is a Berlin based drug delivery company focused on chemical modifications of biological drugs. We offer customized development services for international pharma and biopharma companies and have manufacturing capabilities for key starting materials used for the preparation of pharmaceutical drugs. For the intensification of our own sales activities we are looking for a sales manager. more...

Stock list

All quotes

TOP

  • WILEX3.59 EUR5.59%
  • BASILEA118.10 CHF3.14%
  • PAION2.58 EUR2.79%

FLOP

  • BIOTEST79.20 EUR-19.51%
  • CYTOS1.01 CHF-8.18%
  • FORMYCON28.00 EUR-6.01%

TOP

  • CO.DON3.15 EUR22.1%
  • WILEX3.59 EUR21.3%
  • FORMYCON28.00 EUR21.0%

FLOP

  • CYTOS1.01 CHF-27.9%
  • BIOTEST79.20 EUR-18.1%
  • THERAMETRICS0.07 CHF-12.5%

TOP

  • SANTHERA98.85 CHF2460.9%
  • CYTOS1.01 CHF676.9%
  • WILEX3.59 EUR337.8%

FLOP

  • MOLOGEN5.07 EUR-54.8%
  • THERAMETRICS0.07 CHF-30.0%
  • BIOFRONTERA2.41 EUR-28.1%

No liability assumed, Date: 26.04.2015

Current issue

All issues