SpainSpain

Researchers may retract paper on revolutionary reactome array

04.08.2010

Madrid/Braunschweig - Spanish and German scientists who last year reported a groundbreaking technology that is able to identify the whole set of biochemical reactions in bacteria or cells, together with the enzymes involved, have been recommended to retract their paper (Science, 2009 Oct 9;326(5950):252-7). The Ethics Committee of the Spanish Research Council (CSIC, Madrid) has concluded that the paper describing the ‘reactome array’ should not have been published because controls had not been properly carried out. An official statement detailing the criticism from an additional committee at the German Helmholtz Centre for Infection Research (HIZ, Braunschweig) will be given on 11 August, said a HIZ spokesman. The committees, headed by Pere Puigdomenich (CSIC) and Ronald Frank (HIZ), were established after a number of organic chemists criticised that some of the chemical reactions used to synthesise the fluorescence-quenched metabolites spotted onto the chip were not feasible. However, the recommendation from the CSIC does not say that the array does not function. “We don't know”, said head of the investigation Puigdomenich, speaking to Nature. “We only criticise the way the science in this paper was conducted and reported – we would be happy if someone could validate it.” The lead authors, Peter Golyshin and Manuel Ferrer, were not available for comment. The technique, which has already been used for functional analyses of the metabolic activity of sequenced marine bacteria, promised to be the first experimental tool to help verify computational predictions on the metabolism and function of microorganisms. At this time, all assumptions regarding microbial metabolism are based on DNA sequence analyses. A first-of-its-kind, the reactome array promised to help to unravel through experimentation the functions of hypothetical genes. The CSIC is considering a disciplinary investigation of the scientists involved in the study. It remains open what the recommendations from the HIZ committee and an additional committee involved at the University of Wales in Bangor will contain.

SpainSpain

08.03.2012

Granada-based Integromics S.L. has teamed up with the Galician Foundation of Genomic Medicine (FPGMX) in Santiago de Compostela to secure a €1m EU grant from the European Regional Development Fund and the Spanish government. With...

SpainSpain

08.03.2012

Oryzon Genomics S.A (Barcelona) is entering preclinical testing with a first-in-class bispecific LSD1/MAO-B inhibitor. In addition to the classic target MAO-B, the drug also blocks histone demethylase LSD1, an epigenetic histone...

SpainSpain

06.03.2012

Granada-based nLife Therapeutics S.L. has raised €5m in total from two venture capitalists. Through Caixa Capital Risc and Caixa Capital Biomed, La Caixa invested €2.5m. The same amount has been placed by Invercaria via its...

SpainSpain

05.03.2012

Ordesa Laboratories has filed a patent for a novel Bifidobacterium strain isolated from infant feces. It has the capacity to combat rotavirus, says a study (Appl. Environ. Microbiol., doi:10.1128/AEM.05548).

SpainSpain

19.12.2011

Madrid – Researchers from Spain and the US have discovered an Ebola-like filovirus in bats in northern Spain. The first known filovirus native to Europe was reported in a study published in the journal PLOS Pathogens...

SpainSpain

15.12.2011

Barcelona - South western Europe gets a new R&D unit in the field of biomolecules. Kymos Pharma, a contract researcher based in Barcelona, has signed an agreement with the French biotechnology group Ipsen to create a R&D group...

SpainSpain

12.12.2011

Barcelona/Saffron Walden – Almirall S.A. and BioFocus announced that they have entered into a collaboration agreement to identify new compounds against key targets in projects aimed at the treatment of respiratory and...

SpainSpain

03.12.2011

Madrid/Abu Dhabi – Spanish biotechs are seeking collaborations with firms in the United Arab Emirates. At the end of November, Grupo Zeltia and 14 other Spanish companies presented their research at the forum “Innovation,...

SpainSpain

01.10.2011

Madrid – The Spanish Minister of Innovation and Science Cristina Garmendia has responded to reports about Roche’s­ delivery stop in Greece and pessimistic expectations for Spain. In Sept­ember, she stressed that the atmosphere...

Displaying results 1 to 10 out of 181

1-10 Next >

© 2007-2014 BIOCOM

http://www.european-biotechnology-news.com/news/messages-archive/archive-spain/article/researchers-may-retract-paper-on-revolutionary-reactome-array.html

Events

All Events

Stock list

All quotes

TOP

  • MOLOGEN7.85 EUR5.65%
  • CYTOS0.26 CHF4.00%
  • PAION2.48 EUR2.06%

FLOP

  • 4SC1.25 EUR-2.34%
  • FORMYCON6.75 EUR-1.75%
  • VITA 343.75 EUR-1.57%

TOP

  • SANTHERA83.50 CHF21.8%
  • MAGFORCE6.90 EUR10.8%
  • BB BIOTECH140.45 EUR5.1%

FLOP

  • WILEX2.36 EUR-25.1%
  • MOLOGEN7.85 EUR-19.5%
  • VITA 343.75 EUR-17.6%

TOP

  • SANTHERA83.50 CHF3695.5%
  • CO.DON2.61 EUR226.2%
  • PAION2.48 EUR188.4%

FLOP

  • CYTOS0.26 CHF-93.5%
  • MEDIGENE4.48 EUR-68.1%
  • MERCK KGAA66.20 EUR-43.4%

No liability assumed, Date: 26.08.2014


Current issue

All issues

Product of the week

Products