SpainSpain

Gluten Detection

10.07.2004

Barcelona - The Codex Alimentarius Commission is currently discussing setting the maximum level of gluten for “gluten-free foods” at 20 ppm. This pending threshold is expected to be enforced once an official method for gliadin analysis has been established and progress on “toxicity” related to gluten for coeliac patients has been made. Many food companies have already started to include the new threshold in their quality control procedure.
Ingezim Gluten is a new enzyme immunoassay based on the Double Antibody Sandwich ELISA technique, which uses the R5 monoclonal antibody as its key reagent. The assay was developed by Ingenasa (Immunology and Applied Genetic, SA), a Spanish biotechnology company.
This specific antibody has proven to be strongly reactive to a potential coeliac disease active sequence (QQPFP) present in gliadins and the related prolamins secalin (rye) and hordein (barley). The fact that the antibody does not bind to prolamins of oats (avenin) seems to be advantageous as more and more data suggest that oats do not damage the mucosa of coeliac patients.
The assay is said to be able to detect even the 0.75ng/ml Reference Standard (0.75 ppm of gliadin). Nevertheless, the limit of sensitivity has been set at 1.5 ppm of gliadins in order to ensure a reliability of more than 99%. This detection limit is well under the forthcoming requirements of the Codex Alimentarius Commission.

SpainSpain

08.03.2012

Granada-based Integromics S.L. has teamed up with the Galician Foundation of Genomic Medicine (FPGMX) in Santiago de Compostela to secure a €1m EU grant from the European Regional Development Fund and the Spanish government. With...

SpainSpain

08.03.2012

Oryzon Genomics S.A (Barcelona) is entering preclinical testing with a first-in-class bispecific LSD1/MAO-B inhibitor. In addition to the classic target MAO-B, the drug also blocks histone demethylase LSD1, an epigenetic histone...

SpainSpain

06.03.2012

Granada-based nLife Therapeutics S.L. has raised €5m in total from two venture capitalists. Through Caixa Capital Risc and Caixa Capital Biomed, La Caixa invested €2.5m. The same amount has been placed by Invercaria via its...

SpainSpain

05.03.2012

Ordesa Laboratories has filed a patent for a novel Bifidobacterium strain isolated from infant feces. It has the capacity to combat rotavirus, says a study (Appl. Environ. Microbiol., doi:10.1128/AEM.05548).

SpainSpain

19.12.2011

Madrid – Researchers from Spain and the US have discovered an Ebola-like filovirus in bats in northern Spain. The first known filovirus native to Europe was reported in a study published in the journal PLOS Pathogens...

SpainSpain

15.12.2011

Barcelona - South western Europe gets a new R&D unit in the field of biomolecules. Kymos Pharma, a contract researcher based in Barcelona, has signed an agreement with the French biotechnology group Ipsen to create a R&D group...

SpainSpain

12.12.2011

Barcelona/Saffron Walden – Almirall S.A. and BioFocus announced that they have entered into a collaboration agreement to identify new compounds against key targets in projects aimed at the treatment of respiratory and...

SpainSpain

03.12.2011

Madrid/Abu Dhabi – Spanish biotechs are seeking collaborations with firms in the United Arab Emirates. At the end of November, Grupo Zeltia and 14 other Spanish companies presented their research at the forum “Innovation,...

SpainSpain

01.10.2011

Madrid – The Spanish Minister of Innovation and Science Cristina Garmendia has responded to reports about Roche’s­ delivery stop in Greece and pessimistic expectations for Spain. In Sept­ember, she stressed that the atmosphere...

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