GermanyGermany

High mortality of Argentinian H1N1 influenza virus not linked to dangerous mutations

20.08.2009

Penzberg/New York – The tremendously high mortality of a subtype of the pandemic H1N1 influenza virus strain that killed 6% (EU average 0.2 %) of all patients with a confirmed infection in Argentina is not due to dangerous mutations, according to preliminary analyses of 50 clinical samples with Roche Diagnostics’s (Penzberg, Germany) ultrafast sequencing robots. „We did not find any dangerous mutation, that could explain the high mortality or the occurence of resistance to antiviral drugs such as Tamiflu“, Professor Ian Lipkin from Columbia University (New York) told EuroBiotechNews. With more than 320 fatalities, Argentina has suffered the highest percentage of deaths from the H1N1 2009 virus worldwide.
While a spokesman of the WHO told EuroBiotechNews that this could be due to the fact that the published numbers of confirmed infections allow only a rough estimate about the number of people that really carry the pandemic virus, Lipkin’s team continues to sequence clinical isolates with next generation sequencers. Very preliminary data, which yet need to be verified, point to the possibility that the high mortality may be linked to co-infections with different viruses and bacteria, according to Lipkin, who started the collaborative analysis with Roche, Quintiles and researchers from Argentina’s National Institute of Infectious Diseases at the beginning of August.

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07.03.2012

The first of February marked a milestone for Leverkusen-based Bio­frontera AG in more ways than one. It was the first day that Ameluz, the firm’s first approved product, could be sold in German pharmacies. It was also the date...

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07.03.2012

Darmstadt – German pharmaceutical and chemical company Merck KGaA has set a downbeat tone for 2012. CEO Karl-Ludwig Kley said the recently launched cost-cutting programme and tough economic conditions will weigh on profits this...

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05.03.2012

Mainz/Leuna – Two biotech concepts were amongst the winners of the recent third round of the Excellence Cluster initiative, which is funded by the German Ministry for Research. In Mainz the champagne corks popped especially loud...

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05.03.2012

German Merck KGaA has closed a licencing agreement with US-based Threshold Pharmaceuticals Inc. The cooperation centres around the hypoxia­-activated drug TH-302, which is currently being studied in a global Phase III study....

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29.02.2012

Munich – Looking back with satisfaction and bent on a prize for good behaviour, German biopharmaceutical company Wilex AG reported yesterday on the fiscal year 2011 and outlined the shores in sight. The 2011 total revenue was...

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17.02.2012

Brussels – European cartilage researchers intensify their cooperation. The 'gristle network' comprises scientists from Belgium, France, Germany and Luxembourg. Its members plan to meet regularly to exchange views and information...

27.01.2012

Thousand Oaks/Munich - Bling bling for blinatumomab. It is a compliment for the European life sciences scene and sad news at the same time. Amgen Inc., the world's largest biotechnology company, agreed to buy Micromet Inc., an...

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20.01.2012

Martinsried - SHELTER is responsible for the fact that the stocks of 4SC behaved like a rodeo horse on Thursday. The shares rose in several stages up to 63%, only to settle at a mere 43% rise at the end of the day. SHELTER is a...

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17.01.2012

Ludwigshafen – BASF Plant Science GmbH, the agrochemistry and biotech arm of the world-largest chemistry company, thinks that it has outstayed its welcome in Europe. Over the next two years, most of the green biotechnology...

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10.01.2012

Munich - It is the accolade for Micromet. The German company, which is listed on the U.S. stock exchange, announced today that it has entered into a Cooperative Research and Development Agreement (CRADA) with the renowned US...

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