GermanyGermany

Evotec and Roche terminate proof-of-concept study with EVT101

19.05.2011

Hamburg/Basel – Evotec AG and its partner Roche have terminated the first proof-of-concept study with Evotec’s NR2B sub-type selective NMDA antagonist EVT 101 in treatment-resistant depression.The firms said the move was motivated by difficulties in recruiting patients under the current study protocol, resulting in the possibility of inconclusive results. Furthermore the companies, which collaborate under a potential US$300m deal in phase II development of the drug, said the programme was already delayed due to difficulties in conducting it in treatment resistant depression, the need to sharpen the toxicology profile and a potential requirement for an altered dosage scheme. The clinical co-development of the compound, which Evotec in-licensed from Roche in development stage, was key to the alliance between Evotec and Roche signed in 2009 that was 100% funded by Roche. Evotec retains all rights in the EVT100 series, particularly the back-up compound EVT103, and will enter into partnering discussions for these assets in another clinical development partnership. Recently the Hamburg based firm announced an 54% increase in Q1/2011 (EUR15.1) compared to Q1/2010 (EUR9.8), mainly due to revenues from research alliances.

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07.03.2012

The first of February marked a milestone for Leverkusen-based Bio­frontera AG in more ways than one. It was the first day that Ameluz, the firm’s first approved product, could be sold in German pharmacies. It was also the date...

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07.03.2012

Darmstadt – German pharmaceutical and chemical company Merck KGaA has set a downbeat tone for 2012. CEO Karl-Ludwig Kley said the recently launched cost-cutting programme and tough economic conditions will weigh on profits this...

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05.03.2012

Mainz/Leuna – Two biotech concepts were amongst the winners of the recent third round of the Excellence Cluster initiative, which is funded by the German Ministry for Research. In Mainz the champagne corks popped especially loud...

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05.03.2012

German Merck KGaA has closed a licencing agreement with US-based Threshold Pharmaceuticals Inc. The cooperation centres around the hypoxia­-activated drug TH-302, which is currently being studied in a global Phase III study....

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29.02.2012

Munich – Looking back with satisfaction and bent on a prize for good behaviour, German biopharmaceutical company Wilex AG reported yesterday on the fiscal year 2011 and outlined the shores in sight. The 2011 total revenue was...

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17.02.2012

Brussels – European cartilage researchers intensify their cooperation. The 'gristle network' comprises scientists from Belgium, France, Germany and Luxembourg. Its members plan to meet regularly to exchange views and information...

27.01.2012

Thousand Oaks/Munich - Bling bling for blinatumomab. It is a compliment for the European life sciences scene and sad news at the same time. Amgen Inc., the world's largest biotechnology company, agreed to buy Micromet Inc., an...

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20.01.2012

Martinsried - SHELTER is responsible for the fact that the stocks of 4SC behaved like a rodeo horse on Thursday. The shares rose in several stages up to 63%, only to settle at a mere 43% rise at the end of the day. SHELTER is a...

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17.01.2012

Ludwigshafen – BASF Plant Science GmbH, the agrochemistry and biotech arm of the world-largest chemistry company, thinks that it has outstayed its welcome in Europe. Over the next two years, most of the green biotechnology...

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10.01.2012

Munich - It is the accolade for Micromet. The German company, which is listed on the U.S. stock exchange, announced today that it has entered into a Cooperative Research and Development Agreement (CRADA) with the renowned US...

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