FranceFrance

Transgene inks EUR700m contract with Novartis

11.03.2010

Molsheim/Basel – Novartis AG has secured an exclusive option on a lung cancer vaccine, developed by French drug developer Transgene S.A. Upon clinical proof-of-concept of TG4010, an MVA vector that expresses the cancer antigen MUC1 together with the adjuvans IL-2, the French company can reach milestones up to 700m euros. However investors, who expected a better deal including investments of Novartis for clinical development, pulled down Transgene’s shares by 12%, yesterday. In reality, the deal brings a $10m non-refundable option fee for the company. Transgene has already demonstrated significant time to progression benefit of TG4010 + chemotherapy in a Phase IIb trial in patients with advanced (phase III + IV) non-small cell lung cancer (NSCLC). There was no benefit in overall survival compared to chemotherapy alone, however the company identified a subpopulation, in which more than 70% of patients responded to the treatment. There is strong competition in this field. GlaxoSmithKline and Merck KGaA both have lung cancer vaccines, known as MAGE-A3 and Stimuvax, respectively, in final clinical testing. Transgene intends to initiate Phase III testing of its vaccine at the end of 2010 but can costs back from Novartis if the deal goes ahead.

FranceFrance

28.03.2012

Minneapolis/Banzancourt – Bioamber Inc. is one step closer to the environmental summit. The company's goal is to establish sustainable, "green" chemistry on an industrial scale. The French/US enterprise has now scaled up its...

FranceFrance

14.03.2012

Sophia Antipolis/ Madison – French NicOx S.A. and the global eye health specialist Bausch & Lomb have announced positive top-line results from their phase 2b dose finding study with BOL-303259-X, a nitric oxide-donating version...

FranceFrance

13.03.2012

Paris/Barcelona – French pharma company Sanofi strengthens its ties with the Spanish research institution CGR (Center for Genomic Regulation) in Barcelona. CGR stated on 12 March that the two partners agreed upon three years of...

FranceFrance

06.03.2012

Lyon – The sale of 1.6 million shares brought in €25.3m for French Adocia SAS during its IPO on the Euronext Paris. The price of €15.88 values the diabetes specialist at €96.1m at the upper end of the bookbuilding range. Late...

FranceFrance

05.03.2012

Pointing to a new study on Syngenta’s GM maize Bt11, France’s Environment Ministry has asked the European Commission to suspend authorisation for the use of the MON810 maize sold by US agri­biotech giant Monsanto as well. The...

FranceFrance

27.02.2012

Cambridge - Genzyme will shut the doors at its Cambridge R&D site by the end of the year, with up to 60 employees expected to lose their jobs. The move is part of an ongoing global restructuring of R&D by Sanofi, who purchased...

FranceFrance

07.02.2012

Lille – Shares of the French diabetes specialist Genfit S.A. almost doubled when the company published results of its Phase II study with the PPAR alpha and delta modulator GFT505. The compound has met the co-primary and...

FranceFrance

06.02.2012

Shares of the French diabetes specialist almost doubled when the companypublished results of its Phase II study with the PPAR alpha and deltamodulator GFT505. The compound has met the co-primary and secondaryendpoints while...

FranceFrance

02.02.2012

Bagneux - DBV Technologies is planning an IPO on Euronext Paris. The French pharmaceutical group specialising in the treatment of allergies was founded in 2002. DBV's proprietary technology Viaskin is used to administer an...

FranceFrance

12.01.2012

Berlin/Paris – Sanofi Pasteur has licensed a yeast strain from German Organobalance to produce vaccines. With the deal, the vaccines division of the French drugmaker will gain exclusive access to a modified strain of...

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