FranceFrance

Sanofi Aventis signs miRNA alliance with Regulus Therapeutics

23.06.2010

Strasbourg/Carlsbad – French pharma giant Sanofi-Aventis has secured access to the new drug class of microRNA therapeutics. The company entered a R&D and markting collaboration with Regulus Therapeutics and will pay all R&D and commercialisation costs over three years necessary to develop 4 miRNA targets, including miRNA-21 against fibrosis with an option to extend the collaboration by 2 additional years. Additionally, Regulus will get a US$ 25 million upfront payment, a US$10 million future equity investment subject to mutual agreement on company valuation. Sanofi-Aventis also receives an option for a broader technology alliance worth US$50 million that provides Regulus certain rights to participate in development and commercialisation of resulting products. The joint-venture formed in 2007 by Alnylam Therapeutics and Isis Pharmaceuticals will receive preclinical milestones, development and sales milestones for collaboration targets as well as royalties on microRNA therapeutic products commercialised by Sanofi-Aventis. The alliance is valued at potentially US$750 million in consideration of upfront payments, equity investment, research funding, and potential preclinical, clinical and commercial milestone payments for multiple products if all products are successfully commercialised. Regulus will pay approximately US$4 million of the initial funding to its licensors, the majority of which will be to Isis and Alnylam.

FranceFrance

28.03.2012

Minneapolis/Banzancourt – Bioamber Inc. is one step closer to the environmental summit. The company's goal is to establish sustainable, "green" chemistry on an industrial scale. The French/US enterprise has now scaled up its...

FranceFrance

14.03.2012

Sophia Antipolis/ Madison – French NicOx S.A. and the global eye health specialist Bausch & Lomb have announced positive top-line results from their phase 2b dose finding study with BOL-303259-X, a nitric oxide-donating version...

FranceFrance

13.03.2012

Paris/Barcelona – French pharma company Sanofi strengthens its ties with the Spanish research institution CGR (Center for Genomic Regulation) in Barcelona. CGR stated on 12 March that the two partners agreed upon three years of...

FranceFrance

06.03.2012

Lyon – The sale of 1.6 million shares brought in €25.3m for French Adocia SAS during its IPO on the Euronext Paris. The price of €15.88 values the diabetes specialist at €96.1m at the upper end of the bookbuilding range. Late...

FranceFrance

05.03.2012

Pointing to a new study on Syngenta’s GM maize Bt11, France’s Environment Ministry has asked the European Commission to suspend authorisation for the use of the MON810 maize sold by US agri­biotech giant Monsanto as well. The...

FranceFrance

27.02.2012

Cambridge - Genzyme will shut the doors at its Cambridge R&D site by the end of the year, with up to 60 employees expected to lose their jobs. The move is part of an ongoing global restructuring of R&D by Sanofi, who purchased...

FranceFrance

07.02.2012

Lille – Shares of the French diabetes specialist Genfit S.A. almost doubled when the company published results of its Phase II study with the PPAR alpha and delta modulator GFT505. The compound has met the co-primary and...

FranceFrance

06.02.2012

Shares of the French diabetes specialist almost doubled when the companypublished results of its Phase II study with the PPAR alpha and deltamodulator GFT505. The compound has met the co-primary and secondaryendpoints while...

FranceFrance

02.02.2012

Bagneux - DBV Technologies is planning an IPO on Euronext Paris. The French pharmaceutical group specialising in the treatment of allergies was founded in 2002. DBV's proprietary technology Viaskin is used to administer an...

FranceFrance

12.01.2012

Berlin/Paris – Sanofi Pasteur has licensed a yeast strain from German Organobalance to produce vaccines. With the deal, the vaccines division of the French drugmaker will gain exclusive access to a modified strain of...

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