DenmarkDenmark

Novo Nordisk and Zymo Genetics forge US$182 million antibody deal

10.12.2009

Bagsværd/Seattle – Danish Novo Nordisk has expanded its portfolio of promising biologicals in a multi-million dollar licensing deal with US biotech company ZymoGenetics. Under the terms of the license, Novo Nordisk has agreed to pay ZymoGenetics an initial upfront cash payment of $24 million for its autoimmune and inflammatory antibody therapy IL-21 mAb and has acquired broad intellectual property rights covering IL-21 mAb and the development of other IL-21 antibodies.. In addition, as the development programme of IL-21 mAb advances, ZymoGenetics may receive further milestones from Novo Nordisk of up to US$157.5m. Novo Nordisk in-licensed intellectual property rights to IL-21 antibodies outside North America in 2001 and now has worldwide rights.IL-21 mAb is a preclinical fully-human monoclonal antibody, and a pre-investigational new drug candidate under development for the treatment of autoimmune and inflammatory disorders such as inflammatory bowel disease, rheumatoid arthritis and lupus, in which it is overexpressed. Novo has agreed to pay a $1.5 million milestone payment upon the filing of an Investigational New Drug application, and an $8.5 million milestone payment at the start of phase 1 studies with the mAb. In addition, ZymoGenetics will receive royalties on net sales as the IL-21 mAb development programme advances. As part of the agreement, ZymoGenetics retains the option to fund a portion of phase 3 clinical development costs in exchange for an increased royalty rate on US sales and US co-promotion rights. If ZymoGenetics exercises the option, it would pay a fixed fee of US$10m, together with 15% of the costs of phase 3 clinical trials, and royalties on US sales would increase from single to double digits. (more)

DenmarkDenmark

07.03.2012

Bagsvaerd/Bangalore – Danish Novozymes A/S has begun a new collaboration with Indian Sea6 Energy. The companies will jointly develop enzymes to convert seaweed-based carbohydrates to sugar, which can then be fermented to produce...

DenmarkDenmark

06.03.2012

Prague/Turku/Copenhagen – Danish pharmaceutical company H. Lundbeck A/S yesterday unveiled clinical data on its potential blockbuster drug nalmefene at the 2012 European Congress of Psychiatry clinical in Prague. While Lundbeck...

DenmarkDenmark

05.03.2012

Copenhagen – With the in vitro proof of concept for an undisclosed antibody target, Genmab A/S has reached the second milestone in its collaboration with H. Lundbeck A/S. Genmab will now receive a €1m payment. Under the...

DenmarkDenmark

01.02.2012

Copenhagen/Bangalore – Biofuels need reliable sources of biomass. Novozymes now looks to the ocean to secure biomass. The Danish enzyme specialist announced an exploratory research agreement with Sea6 Energy from India. The...

DenmarkDenmark

02.01.2012

Copenhagen – Hellsinn Healthcare has successfully completed a phase Ib trial in Europe with Zealand Pharma’s GLP-2 (glucagone-like peptide 2) peptide antagonist Elsiglutide (ZP1846). The completion of the study, which was...

DenmarkDenmark

23.12.2011

Copenhagen - An alliance of giants will take a thorough look into biofuels for the maritime sector. The leading enzyme producer Novozymes will team up with parts of the Danish shipping industry, including the world’s largest...

DenmarkDenmark

17.12.2011

Copenhagen/Paris – Danish biopharma­ceuticals company Zealand Pharma A/S has received some positive news. Ever since French partner Sanofi Aventis submitted a marketing authorisation application for Lyxumia (lixisenatide) in...

DenmarkDenmark

07.11.2011

Copenhagen/Paris - The cooperation between Danish biopharmaceutical company Zealand Pharma and French drugmaker Sanofi has borne its first fruit. Sanofi has submitted a marketing authorisation application for Lyxumia...

DenmarkDenmark

01.10.2011

Copenhagen/Ingelheim – Danish HTS expert Nuevolution A/S has signed a license agreement with drugmaker Boeh­ringer Ingelheim (BI). The German pharma company will use Nuevolution’s proprietary Chemetics drug discovery technology...

DenmarkDenmark

25.08.2011

Bagsværd - Novo Nordisk is investing around €134m in a new corporate centre in the Copenhagen suburb Bagsværd. The new office premises will concentrate the top management and 1,100 administrative employees which are currently...

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