DenmarkDenmark

Green light for antibody drug

01.02.2010

Copenhagen – British pharma firm Glaxo­SmithKline and Danish biotech company Genmab finally won European backing for their leukaemia drug Arzerra in January, after the green light for the medicine was given by US regulators in October last year.
Arzerra (Ofatumumab) is the first of Genmab’s drug candidates to reach the market. The European Medicines Agency recommended conditional marketing authorisation for the antibody as treatment for chronic lymphocytic leukaemia in patients who do not respond to Genzyme’s Campath or the chemotherapy drug fludarabine (see p. 12). However, the agency added it wants to see further clinical data about the long-term use of Arzerra, as well as data on a specific group of patients who don’t respond to fludara­bine but can’t be given Campath. GlaxoSmithKline and Genmab are aiming to position Arzerra as a rival to Roche’s and BioGen Idec’s blockbuster treatment Rituxan. GSK bought the global rights to the substance in December 2006 in a deal worth up to US$2.1bn, a record sum for a biotech product at that time. The world’s second largest drugmaker is also banking on Arzerra working in other diseases beyond CLL. But hopes for its use in patients with non-Hodgkin’s lymphoma (NHL) declined last year when a clinical trial failed. According to Thomson Pharma, forecasts for Arzerra suggest annual sales will reach US$465m in 2013.

DenmarkDenmark

07.03.2012

Bagsvaerd/Bangalore – Danish Novozymes A/S has begun a new collaboration with Indian Sea6 Energy. The companies will jointly develop enzymes to convert seaweed-based carbohydrates to sugar, which can then be fermented to produce...

DenmarkDenmark

06.03.2012

Prague/Turku/Copenhagen – Danish pharmaceutical company H. Lundbeck A/S yesterday unveiled clinical data on its potential blockbuster drug nalmefene at the 2012 European Congress of Psychiatry clinical in Prague. While Lundbeck...

DenmarkDenmark

05.03.2012

Copenhagen – With the in vitro proof of concept for an undisclosed antibody target, Genmab A/S has reached the second milestone in its collaboration with H. Lundbeck A/S. Genmab will now receive a €1m payment. Under the...

DenmarkDenmark

01.02.2012

Copenhagen/Bangalore – Biofuels need reliable sources of biomass. Novozymes now looks to the ocean to secure biomass. The Danish enzyme specialist announced an exploratory research agreement with Sea6 Energy from India. The...

DenmarkDenmark

02.01.2012

Copenhagen – Hellsinn Healthcare has successfully completed a phase Ib trial in Europe with Zealand Pharma’s GLP-2 (glucagone-like peptide 2) peptide antagonist Elsiglutide (ZP1846). The completion of the study, which was...

DenmarkDenmark

23.12.2011

Copenhagen - An alliance of giants will take a thorough look into biofuels for the maritime sector. The leading enzyme producer Novozymes will team up with parts of the Danish shipping industry, including the world’s largest...

DenmarkDenmark

17.12.2011

Copenhagen/Paris – Danish biopharma­ceuticals company Zealand Pharma A/S has received some positive news. Ever since French partner Sanofi Aventis submitted a marketing authorisation application for Lyxumia (lixisenatide) in...

DenmarkDenmark

07.11.2011

Copenhagen/Paris - The cooperation between Danish biopharmaceutical company Zealand Pharma and French drugmaker Sanofi has borne its first fruit. Sanofi has submitted a marketing authorisation application for Lyxumia...

DenmarkDenmark

01.10.2011

Copenhagen/Ingelheim – Danish HTS expert Nuevolution A/S has signed a license agreement with drugmaker Boeh­ringer Ingelheim (BI). The German pharma company will use Nuevolution’s proprietary Chemetics drug discovery technology...

DenmarkDenmark

25.08.2011

Bagsværd - Novo Nordisk is investing around €134m in a new corporate centre in the Copenhagen suburb Bagsværd. The new office premises will concentrate the top management and 1,100 administrative employees which are currently...

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