AustriaAustria

Igeneon's IGN101 Vaccine Prolongs Survival of Cancer Patients

10.12.2004

Vienna - The anti-cancer vaccine IGN101 of Austrian Igeneon AG has made an important advance in its clinical development. Results of a phase II trial show a statistically significant survival prolongation in the group of patients with metastatic rectal cancer. Furthermore vaccinations with IGN101 were well tolerated in all indications.
“To have completed this placebo-controlled phase II trial with IGN101 is a major milestone in the development of our lead product candidate,” said Dr. Manfred Ruediger, CEO of Igeneon. Based on the results of this trial, Igeneon is designing a pivotal phase II/III trial with IGN101 to confirm the findings. IGN101 is an active cancer vaccine consisting of the murine monoclonal antibody edrecolomab as vaccine antigen which is designed to prevent or delay the formation of metastases. It is also currently tested in a pivotal phase II/III trial in the second indication, non-small cell lung cancer.
In phase I and phase II trials IGN101 has been shown to induce an immune response, even when administered under concomitant chemotherapy. Igeneon's second most advanced product candidate, the IGN311 monoclonal antibody targeting Lewis Y-positive cancer cells, is expected to complete a phase I trial in 2004.

AustriaAustria

09.03.2012

Breast cancer patients who receive radiation therapy often suffer from inflammation linked to the treatment. Austrian Apeiron Biologics AG is now developing a topical superoxide dismutase treatment (APN201) to try to help these...

AustriaAustria

06.03.2012

The Paracelsus Private Medical University (PMU) in Salzburg is to build a new research center for spinal cord injuries. The €70m construction tab will be picked up by Dietrich Mateschitz, the owner of Red Bull. Other partners in...

AustriaAustria

16.12.2011

Vienna – Two big investors have poured €25m into Austrian vaccine specialist Affiris AG. Venture fund Santo VC – the investment vehicle of German biotech investors Thomas and Andreas Strüngmann – donated €20m, while the German...

AustriaAustria

08.11.2011

Vienna – In Affiris they trust – as a proof of their faith, two big investors poured €25 million into the Austrian developer of a possible Alzheimer drug. Venture fonds Santo VC, the investment vehicle of the German billionaires...

AustriaAustria

17.08.2011

Innsbruck – Austrian specialist for so-called ugimeres, Ugichem GmbH, has landed fresh funding. Along with V+ GmbH and the Austrian Research Promotion Agency, Swiss private investors invested about EUR2m to develop the first...

AustriaAustria

12.08.2011

Innsbruck – An Austrian physician has been fined EUR4,500 in a case involving a controversial stem cell therapy for incontinence. In early August, an Innsbruck Regional Court adjudged Hannes Strasser, who developed the method, at...

AustriaAustria

11.06.2011

Vienna – Nabriva Therapeutics AG, an Austrian specialist for the development of novel antibiotics, has achieved proof-of-concept for its first product in a clinical Phase II study. Called BC-3781, the compound is used to treat...

AustriaAustria

11.06.2011

Vienna – Nabriva Therapeutics AG, an Austrian specialist for the development of novel antibiotics, has achieved proof-of-concept for its first product in a clinical Phase II study. Called BC-3781, the compound is used to treat...

AustriaAustria

28.04.2011

Vienna - f-star, an antibody specialist, today announced the closing of aEUR 15 Million financing. The investment was led by SR One, the corporate venture capital arm of GlaxoSmithKline. All of f-star’s existing investors, Atlas...

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