UKUK

GSK shakes up its R&D

08.02.2012

London - GlaxoSmithKline re-adjusts its €3.7bn R&D budget. Following a review, three of 38 R&D units will be cut and four new ones installed, the UK drug company said in a statement on 7 Februray. Furthermore, six of the discovery units (DPUs) will get more money over the next years, while the budget of five will be cut. The shakeup is the outcome of a review started in November 2011. A panel of GSK executives and external experts heard presentations from the majority of its 38 DPUs. Scientists from each unit told the panel what they want to do over the next three years. In 2008 GSK broke up its R&D operations in tightly knit research groups of five to 70 scientists, who have to win their three-year based on performance. GSK is not the only one to look for a new R&D approach. British-Swedish rival Astra Zeneca hopes on outside innovation. Recently it announced that it will shift the search for external pre-Phase III assets into R&D, in a move to make the more and more important business development more science driven. GSK relies more on in house R&D and thinks it is on the right way. "I am very pleased with the energy, approach and productivity we are seeing from our scientists in these units", says Andrew Witty, CEO of GSK. Indeed, the return rate on the money spent on late stage pipeline projects was 11%. In 2011 it climbed o 12%, and Witty has declared he wants to push that rate to the 14% mark in the near future. Alas, even GSK is not immune against the odds of the pharmaceutical development business. On the same day of the announcement of the R&D successes GSK said that it had paused enrolment in its current Phase IIb clinical trials of GSK2251052 (GSK ‘052) for the treatment of complicated urinary tract infections due to a recently identified microbiological finding.

UKUK

14.11.2011

London – GlaxoSmithKline goes west. The British pharmaceutical company launched the $50-million GSK Canada Life Sciences Innovation Fund that will invest in “early-stage breakthrough research” in health care life science in...

UKUK

04.10.2011

Heidelberg/Cambridge/London– A team of researchers from GlaxoSmithKline, the biotech company Cellzome and from Universities Cambridge, Ulm and Amsterdam have found a promising treatment for mixed lineage (MLL-fusion) leukaemia...

UKUK

01.10.2011

Amersham – GE Healthcare intends to remain a major force in cancer therapy. Based in London, the health business of the US technology giant announced it will be reserving €730m of its total R&D budget over the next five years for...

UKUK

01.10.2011

Wolverhampton – One of the challenges for manufacturers of probiotic foods is getting large enough numbers of the bacteria into the intestines; most perish under the strongly acidic conditions in the stomach. Scientists from the...

UKUK

01.10.2011

Washington – British Shire plc gained more than 10% in late August on the London Stock Exchange after the US FDA approved Firazyr (icatibant) for acute attacks of hereditary angioedema. The compound was developed by Berlin-based...

UKUK

26.09.2011

London – The first clinical trial using human embryonic stem cells will be carried out at the Moorfields Eye hospital in London. Doctors will inject retinal cells into the eyes of 12 patients with Stargardt‘s macular dystrophy, a...

UKUK

20.09.2011

Amersham – GE Healthcare intends to stay a major force in cancer. The health business of the US-technological company, which is based in London, announced to reserve €730m of its total R&D budget over the next five years for...

UKUK

29.08.2011

Cambridge - A new biotech spin off from the University of Cambridge launched with €6.8m venture capital. Newco Mission Therapeutics Ltd. plans to develop cancer drugs targeting enzymes in ubiquitin pathways that control cellular...

UKUK

23.08.2011

London - GlaxoSmithKline has invested about €1.5m to take a 25.4 percent stake in Autifony Therapeutics, a British biotechnology company spun out of GSK to research treatments for tinnitus and hearing loss. Autifony’s other...

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