UKUK

The fifteen-minute genome

07.03.2012

Nanopore sequencer Oxford Nanopore Technologies, a UK firm that promises its third-generation technology could theoretically sequence a human genome in 15 minutes, impressed scientists with the first public presentation of its data on 17 February at the “Advances in Genome Biology and Technology” meeting in Marco Island, Florida (US). The firm’s “Strand sequencing” technology identifies bases in real time by measuring electrical conductivity as a DNA strand is fed through a biological nanopore. The Grid­ION system comprises scalable nodes that contain array chips for multi-nano­pore sequencing of single strands, allowing the user to choose a run time between minutes and days. The initial version, which will be available this year, is designed for real-time sequencing by 2,000 nanopores at once to deliver tens of giga­bits of data per 24 hours. Oxford said that an 8,000-nanopore GridION configuration, which the company asserts could perform whole genome sequencing in 15 minutes, will be available in early 2013. Oxford Nanopore said that GridION will be sold at a price-per-base “as competitive as other leading systems at launch.” The company also said that MinION, a miniature version of the platform, will be available this year. Nano­pore sequencing has the potential to achieve read lengths of up to 10,000 bases, ten times more than the best current platforms. Additionally, the technology promises more cost-effectiveness than current sequencing methods which all are dependent on costly fluorescence cameras and labels. A second application dubbed “Exonuclease sequencing”, which includes enzymatic DNA cleavage, has been partnered with US firm Illumina Inc.

UKUK

17.12.2011

Surrey – The UK government is investing an additional £80m (€93.5m) to fund continued development of the Institute for Animal Health (IAH) at Pirbright, an institute of the Biotechnology and Biological Sciences Research Council...

UKUK

15.12.2011

Rijeka/London – Allergies like asthma or psoriasis might arise from environmental toxins, suggest researchers from Rijeka University (Croatia) and King’s College (London). In mice, they identified a special population of T cells...

UKUK

13.12.2011

London – Interesting times ahead in the European cancer treatment market. A report states that in the UK alone, diagnosis and treatment costs are likely to increase by 62%, from £9.4 billion in 2010 to £15.3 billion by 2021. The...

UKUK

12.12.2011

York - Tissue Regenix Group plc plans to raise €29m through the sale of 181.8 million shares. The regenerative medical device company is held within the IP Group portfolio and a spin-out company from the University of Leeds. The...

UKUK

11.12.2011

London – Cancer Research UK has begun recruiting patients in the first phase of its Stratified Medicine Programme, which is aimed at finding cancer biomarkers and establishing a genetic testing service in the UK. The charity’s...

UKUK

06.12.2011

London – British Prime Minister David Cameron is trying to come to the rescue of Britain’s embattled biopharmaceutical industry. He has earmarked €210m to support a “biomedical catalyst fund” to back early-stage academic and...

UKUK

06.12.2011

London - David Cameron plans to come to the rescue of Britain's embattled biopharmaceutical industry. The conservative prime minister has earmarked £180m (€210 million) to support a "biomedical catalyst fund" to back ...

UKUK

25.11.2011

Cancer Research UK has started recruiting patients in the first phase of its Stratified Medicine Program, which is seeking to find cancer biomarkers and establish a genetic testing service in the U.K. The charity's multi-million...

UKUK

24.11.2011

London – The European Medicines Agency has recalled all batches of the cancer drugs Busilvex, Velcade and Vidaza manufactured at Boehringer Ingelheim’s Ben Venue Laboratories facility in Bedford, Ohio, from the European market....

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