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Stepping across the barrier

06.03.2012

GlaxoSmithKline (GSK) is further strengthening its activity in the area of rare diseases. The London-based pharma giant has signed an early-stage deal to develop and commercialise treatments for lysosomal storage disorders (LSDs). To that end, it has signed a global collaboration with Canadian bio­tech company Angiochem for upwards of US$300m (€223.7m) to help GSK develop blood-brain barrier (BBB)-crossing enzyme replacement therapies that could for the first time address the CNS symptoms of such diseases. The deal will see Montreal-based Angiochem, which specialises in getting peptide compound drugs past the BBB, to create and develop at least one product for a specified LSD. GSK will assume all development and commercial­isation rights to the product. According to Angiochem CEO Jean-Paul Castaign, around 50 rare LSDs have been described so far, and about 20 have central nervous system symptoms that are left unaddressed by current therapies. These are the symptoms that the two companies hope to be able to treat for the first time, along with the peripheral symptoms that to a certain extent can be treated with existing therapies. Angio­chem is also developing brain anti-cancer drugs in partnership with Geron.

UKUK

17.12.2011

Surrey – The UK government is investing an additional £80m (€93.5m) to fund continued development of the Institute for Animal Health (IAH) at Pirbright, an institute of the Biotechnology and Biological Sciences Research Council...

UKUK

15.12.2011

Rijeka/London – Allergies like asthma or psoriasis might arise from environmental toxins, suggest researchers from Rijeka University (Croatia) and King’s College (London). In mice, they identified a special population of T cells...

UKUK

13.12.2011

London – Interesting times ahead in the European cancer treatment market. A report states that in the UK alone, diagnosis and treatment costs are likely to increase by 62%, from £9.4 billion in 2010 to £15.3 billion by 2021. The...

UKUK

12.12.2011

York - Tissue Regenix Group plc plans to raise €29m through the sale of 181.8 million shares. The regenerative medical device company is held within the IP Group portfolio and a spin-out company from the University of Leeds. The...

UKUK

11.12.2011

London – Cancer Research UK has begun recruiting patients in the first phase of its Stratified Medicine Programme, which is aimed at finding cancer biomarkers and establishing a genetic testing service in the UK. The charity’s...

UKUK

06.12.2011

London – British Prime Minister David Cameron is trying to come to the rescue of Britain’s embattled biopharmaceutical industry. He has earmarked €210m to support a “biomedical catalyst fund” to back early-stage academic and...

UKUK

06.12.2011

London - David Cameron plans to come to the rescue of Britain's embattled biopharmaceutical industry. The conservative prime minister has earmarked £180m (€210 million) to support a "biomedical catalyst fund" to back ...

UKUK

25.11.2011

Cancer Research UK has started recruiting patients in the first phase of its Stratified Medicine Program, which is seeking to find cancer biomarkers and establish a genetic testing service in the U.K. The charity's multi-million...

UKUK

24.11.2011

London – The European Medicines Agency has recalled all batches of the cancer drugs Busilvex, Velcade and Vidaza manufactured at Boehringer Ingelheim’s Ben Venue Laboratories facility in Bedford, Ohio, from the European market....

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