Curbing cholesterol can boost antiviral immune response
Edinburgh – Lowering cholesterol could help the body's immune system fight viral infections. According to results presented from Scientists at the University of Edinburgh, the effect is mediated by a type I-interferon signal triggered by virus infection. The researchers demonstrated in mice that cholesterol lowering drugs such as statins could boost an innate immune response. Currently antibiotics target the bug directly. The new approach may lower the rate of resistance mutations because it acts indirectly by mimicking immune signals sent to reduce cholesterol production.