UKUK

British and Serbian scientists look into freezing genes

24.07.2009

Novi Sad/London - EU-funded researchers have identified the genes that allow insects called Arctic springtails to survive temperatures as low as -14°C. 'This is the first in-depth molecular study on the underlying cold survival mechanisms in this species,' commented Melody Clark of the British Antarctic Survey, the lead author of the article. 'Such information is not only of interest to ecologists, but also to the medical field of cryobiology.'
Many species of springtail can survive low temperatures; most achieve this by using the 'freeze avoidance' technique, and some use freeze tolerance. However, the Arctic springtail, Megaphorura arctica, uses a third, rarer technique known as cryoprotective dehydration. As temperatures fall, these tiny creatures dehydrate themselves, taking on the appearance of shrivelled husks in the process. When the weather becomes more clement, the insects rehydrate themselves and resume their normal activities.
The study, published in the journal BMC Genomics (Vol. 10, 2009) was supported in part by the SLEEPING BEAUTY ('Dormancy of cells and organisms-strategies for survival and preservation') project, which is funded under the 'New and Emerging Science and Technology' (NEST) activity area of the Sixth Framework Programme (FP6).
In this study, researchers from the British Antarctic Survey and the University of Novi Sad in Serbia teamed up to identify the genes controlling the processes of dehydration and rehydration. Their analyses revealed that a wide range of genes become active as temperatures fall, including genes controlling the production of a natural antifreeze called trehalose as well as genes involved in tissue and cell remodelling.
When temperatures rise and the springtail recovers, genes involved in energy production, tissue repair and cell division are activated. The findings could have important implications for those working on techniques for preserving cells and tissues at low temperatures for long periods, for example in biobanks.
According to Europe's biobanking project BBMRI (Biobanking and Biomolecular Resources Research Infrastructure), there are currently 300,000+ samples of whole blood, 1.7m of serum, 1.1m of plasma, 8m of FFPE tissue, and 0.5m cryo-conserved samples stored in the 300 EU biobanks.

UKUK

22.12.2011

London - Nothing is well if the end is not well. For Astra Zeneca the end of 2011 isn't well at all. A new anti-ovarian cancer drug and a planned antidepressant have underperformed in tests. As a result, AstraZeneca will take a...

UKUK

17.12.2011

Surrey – The UK government is investing an additional £80m (€93.5m) to fund continued development of the Institute for Animal Health (IAH) at Pirbright, an institute of the Biotechnology and Biological Sciences Research Council...

UKUK

15.12.2011

Rijeka/London – Allergies like asthma or psoriasis might arise from environmental toxins, suggest researchers from Rijeka University (Croatia) and King’s College (London). In mice, they identified a special population of T cells...

UKUK

13.12.2011

London – Interesting times ahead in the European cancer treatment market. A report states that in the UK alone, diagnosis and treatment costs are likely to increase by 62%, from £9.4 billion in 2010 to £15.3 billion by 2021. The...

UKUK

12.12.2011

York - Tissue Regenix Group plc plans to raise €29m through the sale of 181.8 million shares. The regenerative medical device company is held within the IP Group portfolio and a spin-out company from the University of Leeds. The...

UKUK

11.12.2011

London – Cancer Research UK has begun recruiting patients in the first phase of its Stratified Medicine Programme, which is aimed at finding cancer biomarkers and establishing a genetic testing service in the UK. The charity’s...

UKUK

06.12.2011

London – British Prime Minister David Cameron is trying to come to the rescue of Britain’s embattled biopharmaceutical industry. He has earmarked €210m to support a “biomedical catalyst fund” to back early-stage academic and...

UKUK

06.12.2011

London - David Cameron plans to come to the rescue of Britain's embattled biopharmaceutical industry. The conservative prime minister has earmarked £180m (€210 million) to support a "biomedical catalyst fund" to back ...

UKUK

25.11.2011

Cancer Research UK has started recruiting patients in the first phase of its Stratified Medicine Program, which is seeking to find cancer biomarkers and establish a genetic testing service in the U.K. The charity's multi-million...

Displaying results 11 to 20 out of 396

< Previous 11-20 Next >

© 2007-2014 BIOCOM

http://www.european-biotechnology-news.com/nc/news/messages-archive/archive-uk/browse/1/article/british-and-serbian-scientists-look-into-freezing-genes.html

Events

All Events

Stock list

All quotes

TOP

  • MOLOGEN7.85 EUR5.65%
  • CYTOS0.26 CHF4.00%
  • PAION2.48 EUR2.06%

FLOP

  • 4SC1.25 EUR-2.34%
  • FORMYCON6.75 EUR-1.75%
  • VITA 343.75 EUR-1.57%

TOP

  • SANTHERA83.50 CHF21.8%
  • MAGFORCE6.90 EUR10.8%
  • BB BIOTECH140.45 EUR5.1%

FLOP

  • WILEX2.36 EUR-25.1%
  • MOLOGEN7.85 EUR-19.5%
  • VITA 343.75 EUR-17.6%

TOP

  • SANTHERA83.50 CHF3695.5%
  • CO.DON2.61 EUR226.2%
  • PAION2.48 EUR188.4%

FLOP

  • CYTOS0.26 CHF-93.5%
  • MEDIGENE4.48 EUR-68.1%
  • MERCK KGAA66.20 EUR-43.4%

No liability assumed, Date: 26.08.2014


Current issue

All issues

Product of the week

Products