Risen from dead
Bionor Pharma ASA’s development of an HIV vaccine is back on track. In mid-February, the Oslo-based company announced positive results from a Phase IIb study. When combined with antiretroviral treatment, the Vacc-4x vaccine knocked down the viral load in infected patients by 64%. Bionor had already lost hope for the vaccine, and its development was discontinued in 2010 after a previous study failed. Several weeks later, a US researcher reported that the vaccine triggered a plunge in viral load, and levels in patients did not swiftly climb when they were taken off of it. Those results revived Bionor’s hopes, and spurred the company to start the latest confirmatory trial. The positive news makes “a partnering process a natural next step” Bionor announced. The firm is now planning three different new studies for its vaccine.