Philogen cancels IPO after Bayer terminates partnership


Milan/Berlin – Swiss-Italian biotech Philogen SpA has revoked its plan to sell a 23% stake worth EUR65.3m and go public on the Milan stock exchange this Friday. The move came after German Bayer HealthCare unexpectedly terminated an exclusive licence agreement with Philogen involving the firm’s immunocytokine darleukin (L19-IL2). At the time of Bayer’s announcement, the dimeric fusion protein of a fully human scFv which targets the Fibronectin EBD domain which almost exclusively occurs in tumour vasculature and the proinflammatory cytokine IL-2, was tested in two Phase II studies in malignant melanoma. In both, a primary endpoint was objective response rate. A spokesman for Bayer confirmed that it had informed Philogen about its decision to terminate the licensing agreement, but he declined to give any further details.



Rome – The Italian GMO-saga continues. After Italy’s Council of State recently overturned a ban on the cultivation of genetically modified MON810 maize, the political empire is striking back. Federal Minister for Agriculture Luca...



Siena – Roche AG is pursuing Alzheimer therapies developed by Siena Biotech. The Swiss pharma company has decided to exercise an option to become the lead party for the further development and commercialisation of certain...



Arcavacata di Rende (Italy) – Researchers from the University of Calabria have established that activation of the nuclear farnesoid X receptor (FXR) can slow the growth of tamoxifen-resistant breast cancer cells. It is the first...

Switzerland, ItalyItaly


Siena/Basel - Roche has committed to the compounds the Italian outfit Siena Biotech is developing for the use against Alzheimer's disease. The Swiss pharma company will exercise its option to become the lead party for further...



Lainate – Cosmo’s bid for its Italian peer BioXell was successful. At the end of the acceptance period on February 26th, the Italian drug developer traded at the Zurich stock exchange, held 98.96% of all BioXell shares. The offer...



Rome – The Consiglio di Stato, Italy‘s highest court, has overturned the standing ban on the cultivation of genetically modified Mon810 maize. According to the Court, say local papers, Italian farmers do not have to wait with the...



Milan – A court in Milan has given bio­pharmaceutical company MolMed some preliminary breathing space regarding possible patent infringement with MolMed’s cell therapy for the treatment of haematological malignancies (more...)....



Rome – Sigma-Tau S.p.A has achieved promising initial results in a clinical study to evaluate the potential of Zadaxin to increase immune response to the MF59 adjuvanted H1N1 influenza monovalent vaccine Focetria from Novartis....



Lainate – Cosmo Pharmaceuticals has published its public tender offer to acquire all of fellow Italian company Bio­Xell’s outstanding shares. The specialist for optimised generics first offered to buy BioXell for CHF41.3m...



Lainate – Italian company Cosmo Pharmaceuticals SpA has anounced to launch a public tender offer to acquire all outstanding shares of BioXell SpA. According to the pre-announcement, the drug manufacturer’s offer includes a total...

Displaying results 31 to 40 out of 181

< Previous 31-40 Next >

© 2007-2015 BIOCOM


All videos

Product of the week



LentiKat’s offers an unusual investment opportunity

LentiKat’s owns, manufactures and distributes a patented immobilization into lentil-shaped Lentikats Biocatalysts. The unique lentil-like shape of the Lentikats Biocatalyst ensures unlimited diffusion of substrate(s) into any part of the matrix, while still retaining a convenient size for easy separation from the reaction medium. They find application in the Pharma & Food industry (including bio-based chemicals), Wastewater treatment as well as Biofuels. more...


All Events



BioVaria 2015

Job Advert

Sales Manager

celares GmbH is a Berlin based drug delivery company focused on chemical modifications of biological drugs. We offer customized development services for international pharma and biopharma companies and have manufacturing capabilities for key starting materials used for the preparation of pharmaceutical drugs. For the intensification of our own sales activities we are looking for a sales manager. more...

Stock list

All quotes


  • CO.DON2.97 EUR2.41%
  • MOLOGEN5.06 EUR0.80%
  • CYTOS1.28 CHF0.79%


  • MEDIGENE12.90 EUR-11.03%
  • 4SC1.18 EUR-5.60%
  • PAION2.37 EUR-5.58%


  • 4SC1.18 EUR71.0%
  • MEDIGENE12.90 EUR63.9%
  • FORMYCON31.00 EUR31.1%


  • MORPHOSYS60.74 EUR-13.0%
  • BB BIOTECH281.20 EUR-11.2%
  • EPIGENOMICS5.31 EUR-10.6%


  • SANTHERA99.75 CHF2709.9%
  • CYTOS1.28 CHF652.9%
  • FORMYCON31.00 EUR336.6%


  • MOLOGEN5.06 EUR-53.1%
  • PAION2.37 EUR-22.3%
  • BIOFRONTERA2.57 EUR-21.2%

No liability assumed, Date: 18.04.2015

Current issue

All issues