GermanyGermany

National Cancer Institute supports Micromet

10.01.2012

Munich - It is the accolade for Micromet. The German company, which is listed on the U.S. stock exchange, announced today that it has entered into a Cooperative Research and Development Agreement (CRADA) with the renowned US National Cancer Institute (NCI) to develop its lead antibody blinatumomab. “This partnership will enable us to further explore blinatumomab’s clinical potential across a wide range of blood cancers", said Jan Fagerberg, Micromet’s Senior Vice President and Chief Medical Officer Blinatumomab is targeted at patients with acute lymphoblastic leukemia (ALL) and various sub-types of lymphoma. Blinatumomab is the first of Micromet's bispecific BiTE antibodies, designed to harness the body's T cells to kill cancer cells. Under the terms of the agreement, the NCI and Micromet will collaborate on a series of clinical trials to evaluate the safety and efficacy of blinatumomab in patients with B-cell derived hematologic malignancies. The initial NCI-sponsored studies will explore blinatumomab’s utility as a first-line treatment for patients newly diagnosed with ALL, older patients with ALL, and patients with Waldenstrom’s macroglobulinemia.
Additional studies will be designed based on the agreement of both parties. “We are very pleased that the NCI has chosen to support the clinical development of blinatumomab,” said Jan Fagerberg, M.D., Ph.D., Micromet’s Senior Vice President and Chief Medical Officer.and will expand leading U.S. investigators’ experience with the drug."

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