FranceFrance

The stock market celebrates Genfit's Phase II results

07.02.2012

Lille – Shares of the French diabetes specialist Genfit S.A. almost doubled when the company published results of its Phase II study with the PPAR alpha and delta modulator GFT505. The compound has met the co-primary and secondary endpoints while showing no adverse side-effects. It helped to improve insulin sensitivity in the liver and peripheral tissues. It is intended to treat non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH). The product significantly reduced insulin-induced hepatic glucose production by 0.86 mg/kg/min from baseline to week 8 vs. 0.63 mg/kg/min for placebo (p=0.006). The single blinded trial in French centres enrolled 22 insulin-resistant patients with abdominal obesity. GFT505 is the most advanced compound of a group of drug candidates developed by Genfit. It targets multiple risk factors of pre-diabetes and diabetes: hyperglycaemia and insulin resistance, atherogenic dyslipidemia and inflammation, as well as certain liver disorders often associated with pre-diabetic and diabetic states. Genfit was founded in 1999 Loos/France. The company employs about 100 people and is listed at Alternext on the NYSE Euronext Stock Exchange. The biotech still owns global rights to all of its compounds.

FranceFrance

19.08.2011

Marcy l’Etoile – French in vitro diagnostics group Biomérieux S.A. informed the markets that it has acquired Argene, a French company specialising in molecular diagnostics for immuno­compromised patients. Biomérieux said it was...

FranceFrance

17.08.2011

Paris – A team consisting of French scientists and biotech start-up Epixis SA has developed a novel hepatitis C vaccine based on retrovirus-derived virus-like particles (VLPs) pseudotyped with the heterologous viral envelope...

FranceFrance

10.08.2011

Neuilly/New York - Les Laboratoires Servier and Intercept Pharmaceuticals join forces for the development of diabetes drugs. France’s largest independent pharmaceutical company and the US biotech entered into a worldwide ex-U.S....

FranceFrance

20.07.2011

Paris/New Haven - Sanofi pays a $9m milestone payment to Rib-X Pharmaceuticals, Inc. The French pharmaceutical company recently signed worldwide research collaboration and option for license for novel classes of antibiotics...

FranceFrance

12.07.2011

French drug maker Sanofi SA announced mixed results of a late-stage trial of multiple sclerosis drug Lemtrada. The two-year study CARE-MS I is the first of two randomised, Phase 3 clinical trials comparing Sanofi's alemtuzumab to...

FranceFrance

05.07.2011

French Biotech BioAlliance Pharma S.A. has announced plans to raise up toEUR 16.6 million through the sale 3.4 million shares at EUR 4.90 in a rightsissue. The price is a 20% discount to BioAlliance's closing price of EUR6.10...

FranceFrance

14.06.2011

Paris – Pulmonary arterial hypertension (PAH), a severe disease of the arterial blood vessels in the lungs, leads to chronically elevated pulmonary artery pressure and remodelling of the small pulmonary arteries (SMPs) as a...

FranceFrance

11.06.2011

Montpellier – French researchers have identified the factor that renders human dendritic and myeloid cells largely refractory to HIV-1 infection. Overexpression of the SAMHD1 protein in cell culture effectively blocked infection...

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