FranceFrance

The stock market celebrates Genfit's Phase II results

07.02.2012

Lille – Shares of the French diabetes specialist Genfit S.A. almost doubled when the company published results of its Phase II study with the PPAR alpha and delta modulator GFT505. The compound has met the co-primary and secondary endpoints while showing no adverse side-effects. It helped to improve insulin sensitivity in the liver and peripheral tissues. It is intended to treat non-alcoholic fatty liver disease (NAFLD)/non-alcoholic steatohepatitis (NASH). The product significantly reduced insulin-induced hepatic glucose production by 0.86 mg/kg/min from baseline to week 8 vs. 0.63 mg/kg/min for placebo (p=0.006). The single blinded trial in French centres enrolled 22 insulin-resistant patients with abdominal obesity. GFT505 is the most advanced compound of a group of drug candidates developed by Genfit. It targets multiple risk factors of pre-diabetes and diabetes: hyperglycaemia and insulin resistance, atherogenic dyslipidemia and inflammation, as well as certain liver disorders often associated with pre-diabetic and diabetic states. Genfit was founded in 1999 Loos/France. The company employs about 100 people and is listed at Alternext on the NYSE Euronext Stock Exchange. The biotech still owns global rights to all of its compounds.

FranceFrance

17.12.2011

Romainville – Cellectis SA has completed its acquisition of Cellartis AB, which provides stem cell-based in vitro R&D tools, in a cash and stock deal valued at €29.1m (US$39.9m). Cellartis shareholders received 1.9 million...

FranceFrance

01.11.2011

Paris – One of the biggest European biotech deals of 2011 is now sealed. As announced in September, the shareholders of French genome engineering specialist Cellectis approved the takeover of Swedish Cellartis, the European...

FranceFrance

26.10.2011

Paris - Sanofi and MS patients can breathe a sigh of relief. At an MS congress in Amsterdam, the company presented impressive results of a phase III trial comparing alemtuzumab with subcutaneous Rebif interferon beta-1a in 581...

FranceFrance

20.10.2011

Paris/Boulder – French drugmaker Servier has secured the rights for two miroRNA drug candidates from US-biotech MiRagen. Both companies clinched a partnership agreement under which Servier would fund the research, development and...

FranceFrance

10.10.2011

Paris/Hyderabad – Sanofi Aventis believes in India. The pharmaceutical company announced the opening a state-of-the-art vaccine manufacturing facility, believed to be Asia's biggest, in March 2012. In the coming years Sanofi will...

FranceFrance

01.10.2011

Paris – Nanobiotix S.A. is entering the clinical stage with its NanoXray nano­particle therapy, which aims to increase the efficacy of radiotherapy without increasing dosage. In mid-September, the French nano­medicine company...

Sweden, FranceFrance

16.09.2011

Paris – For €16.4m in cash and roughly €12m in shares, French genome engineering specialist Cellectis has taken over Swedish Cellartis. Cellartis is the European leader in stem cell-derived cardiomyocytes and hepatocytes. With 62...

Germany, FranceFrance

09.09.2011

Luxembourg - Disorientation reigns in green biotechnology in Europe. Two decisions by the European Court of Justice regarding genetically modified crops point in different directions. On Thursday the judges left the opponents of...

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