FranceFrance

Sanofi Aventis signs miRNA alliance with Regulus Therapeutics

23.06.2010

Strasbourg/Carlsbad – French pharma giant Sanofi-Aventis has secured access to the new drug class of microRNA therapeutics. The company entered a R&D and markting collaboration with Regulus Therapeutics and will pay all R&D and commercialisation costs over three years necessary to develop 4 miRNA targets, including miRNA-21 against fibrosis with an option to extend the collaboration by 2 additional years. Additionally, Regulus will get a US$ 25 million upfront payment, a US$10 million future equity investment subject to mutual agreement on company valuation. Sanofi-Aventis also receives an option for a broader technology alliance worth US$50 million that provides Regulus certain rights to participate in development and commercialisation of resulting products. The joint-venture formed in 2007 by Alnylam Therapeutics and Isis Pharmaceuticals will receive preclinical milestones, development and sales milestones for collaboration targets as well as royalties on microRNA therapeutic products commercialised by Sanofi-Aventis. The alliance is valued at potentially US$750 million in consideration of upfront payments, equity investment, research funding, and potential preclinical, clinical and commercial milestone payments for multiple products if all products are successfully commercialised. Regulus will pay approximately US$4 million of the initial funding to its licensors, the majority of which will be to Isis and Alnylam.

FranceFrance

05.01.2012

Stockholm/Suresnes - Swedish BioInvent International AB and French Laboratoires Servier are working together on an oncology target. Under the terms of the agreement, Servier will engage BioInvent to screen its proprietary library...

FranceFrance

17.12.2011

Romainville – Cellectis SA has completed its acquisition of Cellartis AB, which provides stem cell-based in vitro R&D tools, in a cash and stock deal valued at €29.1m (US$39.9m). Cellartis shareholders received 1.9 million...

FranceFrance

01.11.2011

Paris – One of the biggest European biotech deals of 2011 is now sealed. As announced in September, the shareholders of French genome engineering specialist Cellectis approved the takeover of Swedish Cellartis, the European...

FranceFrance

26.10.2011

Paris - Sanofi and MS patients can breathe a sigh of relief. At an MS congress in Amsterdam, the company presented impressive results of a phase III trial comparing alemtuzumab with subcutaneous Rebif interferon beta-1a in 581...

FranceFrance

20.10.2011

Paris/Boulder – French drugmaker Servier has secured the rights for two miroRNA drug candidates from US-biotech MiRagen. Both companies clinched a partnership agreement under which Servier would fund the research, development and...

FranceFrance

10.10.2011

Paris/Hyderabad – Sanofi Aventis believes in India. The pharmaceutical company announced the opening a state-of-the-art vaccine manufacturing facility, believed to be Asia's biggest, in March 2012. In the coming years Sanofi will...

FranceFrance

01.10.2011

Paris – Nanobiotix S.A. is entering the clinical stage with its NanoXray nano­particle therapy, which aims to increase the efficacy of radiotherapy without increasing dosage. In mid-September, the French nano­medicine company...

Sweden, FranceFrance

16.09.2011

Paris – For €16.4m in cash and roughly €12m in shares, French genome engineering specialist Cellectis has taken over Swedish Cellartis. Cellartis is the European leader in stem cell-derived cardiomyocytes and hepatocytes. With 62...

Germany, FranceFrance

09.09.2011

Luxembourg - Disorientation reigns in green biotechnology in Europe. Two decisions by the European Court of Justice regarding genetically modified crops point in different directions. On Thursday the judges left the opponents of...

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