Germany, FranceFrance

Micromet seals early stage deal for antibody with Sanofi

31.10.2009

Bethesda/Munich/Paris - Micromet Inc. partnered with sanofi-aventis Group to develop one of the biotech's bispecific T cell engager (BiTE) antibodies for cancer. The Paris-based pharma will pay €8 million up front, and Micromet agreed to take on the discovery, research and development of an antibody targeting an undisclosed antigen found on carcinoma cells through the end of Phase I trials. Micromet gained (13%) on Thursday.
After that, Sanofi will take over, and Micromet will be eligible for up to €312 million in milestones - €162 million for development and regulatory achievements and €150 million for performance-based sales milestones - plus royalties on product sales. BiTE antibodies have been shown to induce an immunological synapse between a T cell and a tumor cell in the same manner as observed during physiological T cell attacks.
Piper Jaffray analyst Edward Tenthoff called it a "huge preclinical discovery deal," even larger than its January agreement with Berlin-based Bayer Schering AG, which paid €4.5 million for a one-year option to a preclinical BiTE antibody for cancer.Under the terms of that collaboration, Bayer has until Jan. 5, 2010, to license an antibody, at which time it will pay an option fee and put Micromet in the path of potential milestone payments of up to €290 million.
Micromet is nominally a US-company and listed at the American Stock Exchange but does all the research from Germany, where it was founded 1993 in Munich.

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05.01.2012

Stockholm/Suresnes - Swedish BioInvent International AB and French Laboratoires Servier are working together on an oncology target. Under the terms of the agreement, Servier will engage BioInvent to screen its proprietary library...

FranceFrance

17.12.2011

Romainville – Cellectis SA has completed its acquisition of Cellartis AB, which provides stem cell-based in vitro R&D tools, in a cash and stock deal valued at €29.1m (US$39.9m). Cellartis shareholders received 1.9 million...

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01.11.2011

Paris – One of the biggest European biotech deals of 2011 is now sealed. As announced in September, the shareholders of French genome engineering specialist Cellectis approved the takeover of Swedish Cellartis, the European...

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26.10.2011

Paris - Sanofi and MS patients can breathe a sigh of relief. At an MS congress in Amsterdam, the company presented impressive results of a phase III trial comparing alemtuzumab with subcutaneous Rebif interferon beta-1a in 581...

FranceFrance

20.10.2011

Paris/Boulder – French drugmaker Servier has secured the rights for two miroRNA drug candidates from US-biotech MiRagen. Both companies clinched a partnership agreement under which Servier would fund the research, development and...

FranceFrance

10.10.2011

Paris/Hyderabad – Sanofi Aventis believes in India. The pharmaceutical company announced the opening a state-of-the-art vaccine manufacturing facility, believed to be Asia's biggest, in March 2012. In the coming years Sanofi will...

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01.10.2011

Paris – Nanobiotix S.A. is entering the clinical stage with its NanoXray nano­particle therapy, which aims to increase the efficacy of radiotherapy without increasing dosage. In mid-September, the French nano­medicine company...

Sweden, FranceFrance

16.09.2011

Paris – For €16.4m in cash and roughly €12m in shares, French genome engineering specialist Cellectis has taken over Swedish Cellartis. Cellartis is the European leader in stem cell-derived cardiomyocytes and hepatocytes. With 62...

Germany, FranceFrance

09.09.2011

Luxembourg - Disorientation reigns in green biotechnology in Europe. Two decisions by the European Court of Justice regarding genetically modified crops point in different directions. On Thursday the judges left the opponents of...

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