FinlandFinland

Genes play a role in lighting up

12.05.2010

Reykjavik – Researchers from the Icelandic bio­tech company deCODE – together with colleagues from 23 institutions in a dozen countries – have determined that genetic factors influence both nico­tine dependence and the incidence of lung cancer. Cigarette smoking is a major cause of illness and death worldwide. The behaviour is a complex one, with variables ranging from how much people smoke to how hard they find it to quit. The impact of long-term smoking on health also varies greatly among individuals. A substantial portion of this variability is genetic, the researchers have now revealed. “Smoking is bad for any­one’s health. But it is even worse for some, and our discoveries continue to strengthen our ability to identify who those people are and give them a compelling additional reason to quit,” said Kári Stefánsson, Executive Chairman at deCODE. Two years ago, deCODE discovered the first common, single-letter variation (SNP) in the sequence of the human genome, on chromosome 15q25, to be associated with nicotine addiction and the risk of lung cancer. Now the scientists have stated that common SNPs on chromo­somes 8p11 and 19q13 among smokers increase the number of cigarettes smoked per day (CPD) – a measure of nicotine addiction – and indicate an increased risk of lung cancer. Published on April 25th in the online edition of Nature Genetics, the study analyses detailed genotypic and smoking data from more than 130,000 participants.

FinlandFinland

11.02.2011

Helsinki – Using laser light to destroy tumour cells lodged in lymphatic vessels can halt the spread of cancer, Finnish researchers headed by Tuomas Tammela have demonstrated. Their approach to destroy the tumour cells, which use...

FinlandFinland

03.11.2010

Turku/Freiburg – EU researchers led by scientists at the University of Turku have begun designing a bacterium able to produce liquefied petroleum gas (LPG) from sunlight. “We have all the parts to put the ability for production...

FinlandFinland

19.09.2010

Rajamäki/Darmstadt – A cooperation project between AB Enzymes Oy and Royal Oy has resulted in the discovery of an enzyme that enables washing temperature to be dropped to as low as 10° C. The project is being funded by the SymBio...

FinlandFinland

08.07.2010

Turku – Finland’s Faron Pharmaceuticals Ltd. has announced a cooperation with German biotech company Priaxon AG to create new scaffold structures to modify the AOC3-protein function and its ligand interaction with orally...

FinlandFinland

09.06.2010

Tampere – Short people are at greater risk of developing heart disease than tall people, according to a meta-analysis of 52 populations-based studies including 3 million people by Finnish researchers (Eur. Heart J.,...

FinlandFinland

11.05.2010

Turku – Finnish Biotie Therapies Corp. confirmed that its oral phospho­diesterase 4 inhibitor ELB353 has proven safe and pharmacologically active in a Phase I study. Pharmacokinetic data point to the suitability of ELB353 for a...

FinlandFinland

07.03.2010

Helsinki/Hinxton – Finland has pledged EUR1.85m to help create world-class bio­informatics, biobanking and translational research infrastructures, the European Bioinformatics Institute (EBI) at the European Molecular Laboratory...

FinlandFinland

04.02.2010

Helsinki –Finland is investing EUR1.9m in creating world class bioinformatics, biobanking and translational research infrastructures. The investment comes as part of the linkage of three large EU projects ELIXIR, BBMRI, and...

FinlandFinland

01.02.2010

Helsinki – The Academy of Finland is restructuring its funding instruments. The purpose of the reform, which will be finalised in fall 2010, is to give greater clarity and flexibility to Finnish researchers, and to improve the...

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