BeNeLuxBelgiumNetherlandsLuxembourg

ThromboGenics in eye drug deal with Novartis unit Alcon

19.03.2012

Leuven – Biopharmaceutical company ThromboGenics has entered into an agreement with Alcon Inc., a division of Novartis for the commercialisation of its product ocriplasmin in all markets outside the U.S. ThromboGenics said it will concentrate on commercialising ocriplasmin in the U.S., where it plans to build its commercial and medical organisation to support the anticipated launch of the eye drug within the next 12 months. The truncated form of the human serine protease plasmin is under review in Europe for the indication symptomatic vitreomacular adhesion. ThromboGenics will receive an up-front payment of €75m and is eligible for a further €90m in potential near-term milestone payments. Additional milestones would bring the potential total of up-fronts and milestones to €375m according to ThromboGenics. The Belgian company will have a "strategic and focused operational role" in the commercialisation of the product in the five largest European markets. The partners will also co-develop ocriplasmin in additional indications, with both companies responsible for development costs. Details were not disclosed. Ocriplasmin is Thrombogenics' lead product. It represents an injectable recombinant microplasmin, a truncated form of the natural human protein plasmin. The drug has successfully completed two Phase III clinical trials for the pharmacological treatment of the eye disease symptomatic vitreomacular adhesion.

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01.09.2011

New York - US-American investment firm OrbiMed announced the closing of a new fund for life science companies in the health sector. The fund acquires healthcare royalty streams and provides structured debt capital to healthcare...

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31.08.2011

Leiden/Stockholm – Dutch Pharming Group NV and Swedish specialist for rare diseases Orphan Biovitrum AB, have launched their recombinant C1 inhibitor Ruconest® in the Netherlands. The launch of the treatment for patients...

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22.08.2011

Leuven – ThromboGenics NV presented promising results of its Ocriplasmin Phase III clinical program at the Annual Meeting of the American Society of Retina Specialists (ASRS). „We remain on track to make regulatory filings for...

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18.08.2011

Liège – A Belgian research team from the University of Liège’s GIGA-Research centre has discovered an unexpected mode of action for the vaccine adjuvant alum. The team discovered that when a vaccine containing alum is injected...

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16.08.2011

Amsterdam – Dutch molecular diagnostics specialist Agendia B.V. postponed its initial public offering in June because of volatile market conditions, revealing that the financing environment for bio­tech firms remains tough....

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11.07.2011

Dutch gene therapy specialist Amsterdam Molecular Therapeutics BV (AMT) has filed a re-examination request for its lead product Glybera. At the end of June, EMA's CHMP recommended against approval of the product to treat...

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12.06.2011

Ghent – The Flanders Institute for Biotechnology VIB will receive EUR3m from the European Commission for the recruitment and training of promising international scientists in the life sciences. This will allow VIB to further...

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12.06.2011

Brussels – Belgian specialist for regenerative medicine TiGenix NV has raised EUR15.2m through the sale of 15.2 million shares at EUR1/share in a rights issue. Existing shareholders, who were eligible to purchase one share for...

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