AustriaAustria

Nabriva clears first big hurdle in proof-of-concept study

11.06.2011

Vienna – Nabriva Therapeutics AG, an Austrian specialist for the development of novel antibiotics, has achieved proof-of-concept for its first product in a clinical Phase II study. Called BC-3781, the compound is used to treat acute bacterial skin and skin structure infections. It is the first substance in a new class of system­ically available pleuromutilin anti­biotics for the treatment of serious skin infections and pneumonia. BC-3781 is being developed for both oral and intravenous formulations. In 207 patients recruited in 23 centers in the US, the study compared two doses of BC-3781 with Vancomycin, the gold standard for drug resistant Gram-positive bacterial skin infections. Nabriva was able to show non-inferiority compared to Vancomycin. Patients receiving BC-3781 in two different dose regimens (100mg and 150mg) showed a similar treatment success compared to Vancomycin. Nabriva is the successor of the Antibiotics Research Institute (ABRI), a former affiliate of Sandoz AG. The decision to spin-out antibiotics research in 2006 followed a strategic re-orientation of the Sandoz unit within the mother company Novartis. Nabriva’s shareholders include a big-name investor syndicate made up of Phase4 Ventures, HBM, The Wellcome Trust, GLSV and the Novartis Venture Fund.

AustriaAustria

03.11.2010

Vienna – Austrian vaccine specialist Intercell AG has landed a new partner for its therapeutic vaccine IC41 against chronic infections with the hepatitis C virus (HCV) after Novartis quit a a 270m partnership with the firm this...

AustriaAustria

16.09.2010

Bremen/Vienna/Galway – A novel protein glue that helps colonies of the barnacle Dosima fascicularis to float on the surface of the water and stick to vessels could inspire the next revolution in medicine and material sciences....

AustriaAustria

18.08.2010

Vienna – Austrian vaccine specialist Intercell AG increased R&D spending by 24% in the second quarter of 2010 to EUR16.9m due to expenditures linked to clinical Phase III testing of its traveller's diarrhoea vaccine. That...

AustriaAustria

19.07.2010

An estimated 20,000 participants from over 185 countries are taking part in the 18th International AIDS Conference that began in Vienna on Sunday. The head of the International AIDS Society, and conference chairman, Julio...

AustriaAustria

14.07.2010

Vienna – Swissmedic has approved IXIARO®, a vaccine against Japanese encephalitis from Intercell AG that is distributed and marketed by Novartis AG. The decision by the Swiss authorities is another important milestone for the...

AustriaAustria

10.07.2010

Vienna – Austria’s Intercell AG has closed the acquisition of Cytos’ platform technology for monoclonal antibody discovery, which is based on expression cloning of monoclonal antibodies from human B-cells. As per agreed terms,...

AustriaAustria

12.05.2010

Vienna – Invoking the EU’s safeguard clause, the Austrian parliament has unanimously instructed its Ministry of Health to establish a specific legal measure to prohibit the cultivation of the biotech potato Amflora in the...

AustriaAustria

07.05.2010

Vienna – Austrian Intercell AG expands its current vaccine business to anti-infective monoclonal antibodies. In a EUR 15 million deal Intercell has bought Cytos' antibody discovery platform technology, the firm announced on 6th...

AustriaAustria

08.03.2010

Vienna – GlaxoSmithKline, the se­cond largest drugmaker in the world, has closed its third drug development cooperation in Vienna in just over a year. After signing agreements with Intercell AG and Affiris GmbH, GSK is now to pay...

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No liability assumed, Date: 19.10.2014


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