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Apeiron strikes again

17.03.2011

Vienna – Apeiron Biologics has entered into an exclusive option with the Cleveland Clinic to license a number of novel compounds that are currently in development there. The drug candidates are designed to fight cancer by stimulating the immune system. The transaction follows in the wake of other successful in-licensing deals that Apeiron has completed in the last six months. The collaboration includes an option for Apeiron to enter into a worldwide, exclusive licensing agreement with the Cleveland Clinic relating to the compounds, and a research agreement sponsored by Apeiron relating to these compounds and approach. The approach involves tyrosine phosphatase inhibitors (TPI) inhibiting SHP-1, a protein tyrosine phosphatase that is a key negative regulator of immune cell activation. Inhibition of SHP-1 leads to activation of the immune system to combat cancer. Apeiron CEO Hans Loibner called the deal a “great collaboration for Apeiron,“ adding that he regards the compounds developed at the Cleveland Clinic as “an attractive opportunity, since they are designed to activate the patient’s own immune system.” Loibner has been a specialist for immune therapies in oncology for more than twenty years. Apeiron will also close a financing round to fund the development of its clinical pipeline.

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03.11.2010

Vienna – Austrian vaccine specialist Intercell AG has landed a new partner for its therapeutic vaccine IC41 against chronic infections with the hepatitis C virus (HCV) after Novartis quit a a 270m partnership with the firm this...

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16.09.2010

Bremen/Vienna/Galway – A novel protein glue that helps colonies of the barnacle Dosima fascicularis to float on the surface of the water and stick to vessels could inspire the next revolution in medicine and material sciences....

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18.08.2010

Vienna – Austrian vaccine specialist Intercell AG increased R&D spending by 24% in the second quarter of 2010 to EUR16.9m due to expenditures linked to clinical Phase III testing of its traveller's diarrhoea vaccine. That...

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19.07.2010

An estimated 20,000 participants from over 185 countries are taking part in the 18th International AIDS Conference that began in Vienna on Sunday. The head of the International AIDS Society, and conference chairman, Julio...

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14.07.2010

Vienna – Swissmedic has approved IXIARO®, a vaccine against Japanese encephalitis from Intercell AG that is distributed and marketed by Novartis AG. The decision by the Swiss authorities is another important milestone for the...

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10.07.2010

Vienna – Austria’s Intercell AG has closed the acquisition of Cytos’ platform technology for monoclonal antibody discovery, which is based on expression cloning of monoclonal antibodies from human B-cells. As per agreed terms,...

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12.05.2010

Vienna – Invoking the EU’s safeguard clause, the Austrian parliament has unanimously instructed its Ministry of Health to establish a specific legal measure to prohibit the cultivation of the biotech potato Amflora in the...

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07.05.2010

Vienna – Austrian Intercell AG expands its current vaccine business to anti-infective monoclonal antibodies. In a EUR 15 million deal Intercell has bought Cytos' antibody discovery platform technology, the firm announced on 6th...

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08.03.2010

Vienna – GlaxoSmithKline, the se­cond largest drugmaker in the world, has closed its third drug development cooperation in Vienna in just over a year. After signing agreements with Intercell AG and Affiris GmbH, GSK is now to pay...

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